中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
长春应用化学研究所 [1]
采集方式
OAI收割 [6]
内容类型
期刊论文 [6]
发表日期
2023 [1]
2021 [1]
2020 [1]
2019 [1]
2018 [1]
2011 [1]
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Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:
Hu, Xianglong
;
Xun, Qiuju
;
Zhang, Tao
;
Zhu, Su-Jie
;
Li, Qian
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2020/07/01
EGFR(C797S) mutant
SARs
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidine
Clinical resistance
Fourth-generation inhibitors
Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR(L858R/T790M/C797S)
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 6, 页码: 869-873
作者:
Li, Qiannan
;
Zhang, Tao
;
Li, Shiliang
;
Tong, Linjiang
;
Li, Junyu
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
EGFR
mutant
inhibitor
C797S
Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 11, 页码: 1123-1127
作者:
Lu, Xiaoyun
;
Zhang, Tao
;
Zhu, Su-Jie
;
Xun, Qiuju
;
Tong, Lingjiang
  |  
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2019/01/08
EGFR(C797s)
Clinical resistance
Fourth-generation nhibitors
Monodrug efficacy
Studying the interaction of carbohydrate-protein on the dendrimer-modified solid support by microarray-based plasmon resonance light scattering assay
期刊论文
OAI收割
analyst, 2011, 卷号: 136, 期号: 20, 页码: 4301-4307
Li XM
;
Gao JQ
;
Liu DJ
;
Wang ZX
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2012/06/12
CAPILLARY AFFINITY ELECTROPHORESIS
GOLD NANOPARTICLE PROBES
CONCANAVALIN-A
CELL-INTERACTIONS
N-GLYCANS
BINDING
SURFACE
LECTINS
RECOGNITION
LIGANDS