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BMAL1/PGC1a4-FNDC5/irisin axis impacts distinct outcomes of time-of-day resistance exercise
期刊论文
OAI收割
JOURNAL OF SPORT AND HEALTH SCIENCE, 2025, 卷号: 14, 页码: 23
作者:
Guo, Mingwei
;
Shen, Fei
;
Guo, Xiaozhen
;
Zhang, Jun
;
Ma, Ying
  |  
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2025/04/01
Daily variance
Circadian
Muscle strength
Metabolic benefits
Resistance exercise
Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 14
作者:
Tian, Lina
;
Xiao, Jian
;
Zeng, Yanping
;
Li, Yangsha
;
Wei, Aihuan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
CDK9
EZH2
Dual target inhibitor
DLBCL
Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:
Zheng, Fuqiang
;
Hu, Zhengtao
;
Chen, Hai
;
Cheng, Jiaxin
;
Hou, Qiongqiong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/06/23
Heterocycle-fused phenylcyclohexylamines
Multi-target antagonists
NMDAR
Monoamine transporter
Antidepressants
The Overview and Trial Observations of AIMS
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Deng, Yuanyong
;
Wang, Dongguang
;
Hua, Jianwen
;
Xu, Songbo
;
Liang, Ming
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/07/14
Sun: infrared
methods: observational
instrumentation: spectrographs
Cryo- EM structures of GnRHR: Foundations for next- generation therapeutics
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2025, 卷号: 122, 期号: 25, 页码: 10
作者:
Shen, Shiyi
;
He, Xinheng
;
Liu, Heng
;
Hu, Wen
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
GnRHR
reproductive health
therapeutic target
Cryo-EM Structure
Identification of Cannabigerol-Derived Dual CB
2
Receptor Agonists and TRPM8 Antagonists with Anti-Inflammatory and Analgesic Activities
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 13, 页码: 13335-13357
作者:
Yang, Wenjiao
;
Sun, Haiguo
;
Ji, Jing
;
Chen, Hai
;
Cheng, Jiaxin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 20
作者:
Zhao, Wenfeng
;
Chen, Guofeng
;
He, Jian
;
Shen, Xiaofang
;
Xiong, Muya
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Gravitational wave astronomy with TianQin
期刊论文
OAI收割
REPORTS ON PROGRESS IN PHYSICS, 2025, 卷号: 88, 期号: 5
作者:
Li, En-Kun
;
Liu, Shuai
;
Torres-Orjuela, Alejandro
;
Chen, Xian
;
Inayoshi, Kohei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/05/26
gravitational wave
astronomy
TianQin
Design and Development of a Novel Oral 4′-Fluorouridine Double Prodrug VV261 against SFTSV
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 9, 页码: 9811-9826
作者:
Cheng, Yong
;
Zheng, Wei
;
Dong, Xinru
;
Sun, Tengxiao
;
Xu, Mengwei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/06/23
Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796
作者:
Hu, Liuyan
;
Zhao, Zhi
;
Zhang, Shujing
;
Yang, Lei
;
Cui, Wenjie
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/06/23
COVID-19
SARS-CoV-2
3CL protease
Peptidomimetic inhibitors
Tetrahydropyrrole spirodihydroindolone