机构

• 上海药物研究所 [190]
• 金属研究所 [2]
• 新疆理化技术研究所 [2]
• 中国科学院大学 [2]
• 心理研究所 [1]
• 深海科学与工程研究所 [1]
• 更多

采集方式

• OAI收割 [196]
• iSwitch采集 [2]

内容类型

• 期刊论文 [196]
• 会议论文 [2]

发表日期

• 2025 [4]
• 2024 [2]
• 2023 [8]
• 2022 [5]
• 2021 [11]
• 2020 [5]
• 更多

学科主题

• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共198条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Design, Synthesis, and Biological Evaluation of Pyrrolo[1,2-a]quinoxalin-4(5H)-one Derivatives as Potent and Orally Available Noncovalent Bruton's Tyrosine Kinase (BTK) Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8841-8860 作者:  Tian, Chaoquan;  Du, Husheng;  Sha, Wenjie;  Wu, Lingkang;  Yu, Zhixiao   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/05/27 IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19 作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei   |  收藏  |  浏览/下载：27/0  |  提交时间：2025/04/01 Acute myeloid leukemia  HDAC inhibitor  FLT3-ITD mutation  DNA damage response  Synergistic effect  Drug resistance   Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 19 作者:  Yin, Wen   |  收藏  |  浏览/下载：36/0  |  提交时间：2025/04/01 Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia 期刊论文  OAI收割 CANCER RESEARCH, 2025, 卷号: 85, 期号: 1, 页码: 101-117 作者:  Luo, Ziwei;  Lin, Chencen;  Yu, Chuwei;  Yuan, Changxian;  Wu, Wenyong   |  收藏  |  浏览/下载：37/0  |  提交时间：2025/02/28 Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS-mutant Cancers 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 20 作者:  Wang, Yafang;  Xu, Lansong;  Ling, Lijun;  Yao, Mingyue;  Shi, Shangxuan   |  收藏  |  浏览/下载：37/0  |  提交时间：2024/10/21 KRAS  CDK9  ERK  complement activation  immunosuppression   Combination of miR159 Mimics and Irinotecan Utilizing Lipid Nanoparticles for Enhanced Treatment of Colorectal Cancer 期刊论文  OAI收割 PHARMACEUTICS, 2024, 卷号: 16, 期号: 4, 页码: 18 作者:  Yang, Rulei;  Liu, Yiran;  Yang, Ning   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/05/31 colorectal cancer  plant-derived miR159  irinotecan  lipid nanoparticle   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：58/0  |  提交时间：2024/03/25 A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10 作者:  Zhang, Yumin;  Sun, Yuan;  Xie, Yuanchao;  Shang, Weijuan;  Wang, Zhen   |  收藏  |  浏览/下载：32/0  |  提交时间：2023/12/08 Selective Electrochemical Benzylic C(sp(3))-H Oxidations in Fluoroalcohols 期刊论文  OAI收割 CHEMISTRYSELECT, 2023, 卷号: 8, 期号: 27, 页码: 4 作者:  Shen, Haiwei;  Yang, Bo;  Lin, Jiusheng;  Zheng, Mingyue;  Jiang, Hualiang   |  收藏  |  浏览/下载：51/0  |  提交时间：2023/10/17 C(sp(3))-H oxidation  electrochemical  aryl aldehydes  fluorinated ethers  eco-friendly   Synthesis, cytotoxicity, and pharmacokinetic evaluations of niclosamide analogs for anti-SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 11 作者:  Li, Rui   |  收藏  |  浏览/下载：34/0  |  提交时间：2023/10/17 SARS-CoV-2  Niclosamide analogs  Cytotoxicity  Pharmacokinetic  SKP2 inhibition