中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [64]
长春光学精密机械与... [61]
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期刊论文 [503]
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Biochemis... [14]
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UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 237, 页码: 19
作者:
Wang, Li
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Bao, Xu-Bin
;
Tian, Chang-Qing
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
UBE4B
BET inhibitors
Resistance
KLHL22
JAK2
The combination of BET and METTL3 inhibitors elicits synergistic antitumor effects in ovarian cancer cells
via
reducing SP1 and BCL-2 expression
期刊论文
OAI收割
LIFE SCIENCES, 2025, 卷号: 368, 页码: 14
作者:
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
BET inhibitor
METTL3 inhibitor
Combination therapy
SP1
BCL-2
A Phase I Study to Evaluate the Pharmacokinetics and Safety of TPN171 (a PDE5 Inhibitor) in Adults with Renal Impairment
期刊论文
OAI收割
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2025, 页码: 8
作者:
Fu, Ping
;
Song, Yi
;
Hu, Chao
;
Yong, Xiaolan
;
Yu, Yang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/23
pharmacokinetics
phosphodiesterase 5 inhibitor
renal impairment
safety
TPN171
USP7 V517F mutation as a mechanism of inhibitor resistance
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 14
作者:
Miao, Yu-Ling
;
Fan, Fengying
;
Cheng, Yong-Jun
;
Jia, Li
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/05/27
Research on 3D Reconstruction Methods for Incomplete Building Point Clouds Using Deep Learning and Geometric Primitives
期刊论文
OAI收割
REMOTE SENSING, 2025, 卷号: 17, 期号: 3, 页码: 399
作者:
Ding, Ziqi
;
Lu, Yuefeng
;
Shao, Shiwei
;
Qin, Yong
;
Lu, Miao
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/03/18
three-dimensional reconstruction
point cloud processing
deep learning
point cloud completion
Method for Evaluating Urban Building Renewal Potential Based on Multimachine Learning Integration: A Case Study of Longgang and Longhua Districts in Shenzhen
期刊论文
OAI收割
LAND, 2025, 卷号: 14, 期号: 1, 页码: 15
作者:
Sun, Dengkuo
;
Lu, Yuefeng
;
Qin, Yong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/02/24
urban renewal
potential assessment
multimodel fusion
micro-level analysis
Shenzhen
Evaluating Sustainable Development in the Middle and Lower Reaches of the Yellow River Basin Using Multiple Data Sources
期刊论文
OAI收割
IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING, 2025, 卷号: 63, 页码: 4400518
作者:
Lu, Yuefeng
;
Li, Jing
;
Song, Zhenqi
;
Lu, Miao
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/02/24
Rivers
Indexes
Sustainable development
Socioeconomics
Remote sensing
Water resources
Urban areas
Soil
Biological system modeling
Surface treatment
Ecological environment
influencing factors
middle and lower reaches of the Yellow River Basin
social economy
sustainable development
Research on Desertification Monitoring and Vegetation Refinement Extraction Methods Based on the Synergy of Multisource Remote Sensing Imagery
期刊论文
OAI收割
IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING, 2025, 卷号: 63, 页码: 4404819
作者:
Song, Zhenqi
;
Lu, Yuefeng
;
Yuan, Jinhui
;
Lu, Miao
;
Qin, Yong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/21
Desertification difference index (DDI)
hue-saturation-lightness greenway enhanced vegetation index (HSLGEVI)
multisource remote sensing collaborative monitoring
normalized difference vegetation index (NDVI)- albedo feature space
normalized difference vegetation index (NDVI)- albedo feature space
vegetation refinement extraction
vegetation refinement extraction
vegetation refinement extraction
Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 277, 页码: 17
作者:
Zhuang, Zhen
;
Miao, Yu-Ling
;
Song, Shan-Shan
;
Leng, Guang-Tong
;
Zhang, Xiao-Fei
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/09/26
USP7 inhibitor
Structure-activity relationships
Anti-cancer
pyrrolo[2,3-d]pyrimidin-4-one
Mechanical Behavior of Natural Granite Residual Soil in Simple Shear
期刊论文
OAI收割
JOURNAL OF GEOTECHNICAL AND GEOENVIRONMENTAL ENGINEERING, 2024, 卷号: 150, 期号: 10, 页码: 17
作者:
Liu, Xinyu
;
Miao, Yu
;
Zhang, Xianwei
;
Yin, Song
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/06/27
Granite residual soil
Simple shear
Hollow-cylinder torsional shear
Shear strength
Stiffness
Soil structure