中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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西北高原生物研究... [138]
昆明植物研究所 [126]
上海药物研究所 [114]
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共1616条,第1-10条
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Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
期刊论文
OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:
Bian, Yi-cong
;
Meng, Jian
;
Hu, Tao
;
Ma, Sheng
;
Huang, Chen-rong
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
HSK7653
long-acting dipeptidyl peptidase-4 inhibitor
mass balance
metabolism
pharmacokinetics
radiolabelled
NICER, NuSTAR, and Insight-HXMT Views to Black Hole X-Ray Binary SLX 1746-331
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2024, 卷号: 965, 期号: 2
作者:
Peng, Jing-Qiang
;
Zhang, Shu
;
Shui, Qing-Cang
;
Zhang, Shuang-Nan
;
Chen, Yu-Peng
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/04/22
Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 17
作者:
Pu, Congying
;
Li, Yize
;
Fu, Yixian
;
Yan, Yiyang
;
Tao, Siyao
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/02/27
AIM2 inflammasome
chemotherapy
gut microbiome
ileal epithelial cells
immune checkpoint blockade
lactobacillus
segmented filamentous bacterium
Scallop-bacteria symbiosis from the deep sea reveals strong genomic coupling in the absence of cellular integration
期刊论文
OAI收割
ISME JOURNAL, 2024, 卷号: 18, 期号: 1, 页码: 14
作者:
Lin, Yi-Tao
;
Ip, Jack Chi-Ho
;
He, Xing
;
Gao, Zhao-Ming
;
Perez, Maeva
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
chemosynthesis
cold seep
ectosymbiosis
glass scallop
thiotrophy
Rapid Determination of Positive-Negative Bacterial Infection Based on Micro-Hyperspectral Technology
期刊论文
OAI收割
SENSORS, 2024, 卷号: 24, 期号: 2
作者:
Du, Jian
;
Tao, Chenglong
;
Qi, Meijie
;
Hu, Bingliang
;
Zhang, Zhoufeng
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/04
micro-hyperspectral technology
bacterial infection
positive-negative determination
spectral feature
directly smeared urine sample
deep learning
Divergent climatic effects on forest greenness modulated by temperature and precipitation gradients in the Yellow River Basin, China
期刊论文
OAI收割
ECOLOGICAL INDICATORS, 2024, 卷号: 158, 页码: 10
作者:
Tao, Jian
;
Xu, Yuqian
;
Cong, Nan
;
Li, Chanjuan
;
Zhao, Guangshuai
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/25
Forest greenness
Leaf area index
Water resource limitation
Climate warming
NICER, NuSTAR, and Insight-HXMT Views to the Newly Discovered Black Hole X-Ray Binary Swift J1727.8-1613
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2024, 卷号: 960, 期号: 2
作者:
Peng, Jing-Qiang
;
Zhang, Shu
;
Shui, Qing-Cang
;
Zhang, Shuang-Nan
;
Kong, Ling-Da
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/29
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
DRS: A deep reinforcement learning enhanced Kubernetes scheduler for microservice-based system
期刊论文
OAI收割
SOFTWARE-PRACTICE & EXPERIENCE, 2023, 页码: 25
作者:
Jian, Zhaolong
;
Xie, Xueshuo
;
Fang, Yaozheng
;
Jiang, Yibing
;
Lu, Ye
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/04
deep reinforcement learning
Kubernetes scheduler
microservice scheduling
resource awareness