机构

• 上海药物研究所 [7]
• 近代物理研究所 [6]
• 动物研究所 [4]
• 半导体研究所 [3]
• 化学研究所 [2]
• 地球化学研究所 [2]
• 更多

采集方式

• OAI收割 [37]
• iSwitch采集 [2]

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筛选

浏览/检索结果: 共39条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2025, 页码: 14 作者:  Wen, Yiming;  Xu, Peijia;  Chen, Yijie;  Meng, Jingyi;  Zheng, Mingyue   |  收藏  |  浏览/下载：12/0  |  提交时间：2025/04/01 p53 Y220C  Covalent stabilizer  Virtual screening  Molecular dynamics  DNA binding  Structure-activity relationship  Cancer therapy   Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel HsClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307 作者:  Sun, Mingyang;  Chen, Beijing;  Teng, Dan;  Zhao, Hongshen;  Liao, Yilie   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/04/01 Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21 作者:  Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/12/25 Synthetic lethal  MSI tumors  WRN inhibitors  Triazolo-pyrimidine derivatives   Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21 作者:  Chen, Beijing;  Sun, Mingyang;  Zhang, Chun;  Huang, Qi;  Teng, Dan   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/12/25 Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseases 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2024, 页码: 14 作者:  Zhang, Yinghui;  Liu, Yadan;  Jiang, Bing;  Chen, Lifan;  Hu, Jie   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/10/21 cGAS-STING signaling  STING inhibitor  TransformerCPI model  Licochalcone D  inflammatory diseases   Population structure and breed identification of Chinese indigenous sheep breeds using whole genome SNPs and InDels 期刊论文  OAI收割 GENETICS SELECTION EVOLUTION, 2024, 卷号: 56, 期号: 1 作者:  Zhao, Chang-heng;  Wang, Dan;  Yang, Cheng;  Chen, Yan;  Teng, Jun   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/11/27 Magnetic and transport properties in antiferromagnetic antiperovskite Eu3SnO 期刊论文  OAI收割 PHYSICAL REVIEW MATERIALS, 2023, 卷号: 7, 期号: 7, 页码: 7 作者:  Li, Mingze;  Han, Dan;  Wang, Zhenhua;  Li, Bing;  Yang, Teng   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/01/08 Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract 期刊论文  OAI收割 CANCER COMMUNICATIONS, 2022 作者:  Wu, Huanwen;  Yu, Zicheng;  Liu, Yueping;  Guo, Lei;  Teng, Lianghong   |  收藏  |  浏览/下载：44/0  |  提交时间：2022/12/22 Neuroendocrine carcinomas  Gastrointestinal tract  Genomic characterization  Heterogeneity  Therapeutic implications   Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: D1, 页码: D27-D38 作者:  Xue, Yongbiao;  Bao, Yiming;  Zhang Zhang;  Zhao, Wenming;  Xiao, Jingfa   |  收藏  |  浏览/下载：125/0  |  提交时间：2022/04/02 Database Resources of the National Genomics Data Center,China National Center for Bioinformation in 2022 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 页码: 27-38 作者:  Xue Yongbiao;  Bao Yiming;  Zhang Zhang;  Zhao Wenming;  Xiao Jingfa   |  收藏  |  浏览/下载：103/0  |  提交时间：2023/04/17