中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Pharmacokinetics, mass balance, and metabolism of [
14
C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12
作者:
Gao, Lei
;
Ma, Sheng
;
Yan, Shu
;
Zhang, Hua
;
Tian, Ling
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/07/25
FCN-437c
CDK4/6 inhibitor
Mass balance
Radiopharmacokinetics
Drug metabolism
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Concise synthesis of NDP-activated uronic acid by an oxidation reaction insertion strategy
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2025, 卷号: 36, 期号: 8, 页码: 7
作者:
Yang, Nana
;
Yuan, Rui
;
Fu, Xinyue
;
Tian, Xiao
;
Yu, Jin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
NDP-uronic acids
Biocatalysis
Enzyme-mediated biomimetic synthesis
Oxidation reaction insertion strategy
Guiding precision medicine strategy for intravenous ginsenosides via pharmacokinetic-informed bioinformatic approaches: a study on XueShuanTong
期刊论文
OAI收割
PHYTOMEDICINE, 2025, 卷号: 143, 页码: 18
作者:
Jia, Wei-Wei
;
Tian, Nan-Nan
;
Song, Zi-Jing
;
Lan, Xiao-Fang
;
Yang, Xi-He
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Precision medicine
Physiologically based pharmacokinetic model
Ginsenoside
Albumin-facilitated dissociation
Drug interaction
Drug transporter
Hepatic impairment
Bright Bursts with Submillisecond Structures of FRB 20230607A in a Highly Magnetized Environment
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1
作者:
Zhou, DeJiang
;
Han, J. L.
;
Zhang, Bing
;
Zhu, WeiWei
;
Wang, Wei-yang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/07/28
Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:
Zheng, Fuqiang
;
Hu, Zhengtao
;
Chen, Hai
;
Cheng, Jiaxin
;
Hou, Qiongqiong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/06/23
Heterocycle-fused phenylcyclohexylamines
Multi-target antagonists
NMDAR
Monoamine transporter
Antidepressants
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
The possible "double-bang firecracker" during a solar prominence eruption
期刊论文
OAI收割
Science China: Physics, Mechanics and Astronomy, 2025, 卷号: 68, 期号: 7
作者:
Zheng, Ruisheng
;
Liu, Yihan
;
Zhong, Ze
;
Zhang, Liang
;
Wang, Xiaoqian
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/06/10
solar prominence eruptions
coronal mass ejections
coronal pseudostreamers
magnetic reconnecti
Stable isotope tracing the transformation dynamics of diverse water bodies in the Manas River Basin, Northwest China
期刊论文
OAI收割
APPLIED WATER SCIENCE, 2025, 卷号: 15, 期号: 7, 页码: 156
作者:
Zhang, Heng
;
Tian, Lijun
;
Tian, Hao
;
Farid, Muhammad Arsalan
;
Li, Xiaolong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/07/18
Manas River Basin
Hydrogen and oxygen isotopes
Precipitation
Surface water
Groundwater
MixSIAR model
Identification of Cannabigerol-Derived Dual CB
2
Receptor Agonists and TRPM8 Antagonists with Anti-Inflammatory and Analgesic Activities
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 13, 页码: 13335-13357
作者:
Yang, Wenjiao
;
Sun, Haiguo
;
Ji, Jing
;
Chen, Hai
;
Cheng, Jiaxin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20