中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
近代物理研究所 [30]
上海药物研究所 [10]
西北高原生物研究所 [9]
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期刊论文 [116]
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Tofacitinib prevents depressive-like behaviors through decreased hippocampal microgliosis and increased BDNF levels in both LPS-induced and CSDS-induced mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Gao, Ya-nan
;
Pan, Kai-jun
;
Zhang, Yong-mei
;
Qi, Ying-bei
;
Chen, Wen-gang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/05
tofacitinib
depression
JAK-STAT pathway
microgliosis
synaptic defects
Ancient genomes revealed the complex human interactions of the ancient western Tibetans
期刊论文
OAI收割
CURRENT BIOLOGY, 2024, 卷号: 34, 期号: 12, 页码: 20
作者:
Bai, Fan
;
Liu, Yichen
;
Wangdue, Shargan
;
Wang, Tianyi
;
He, Wei
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2025/01/03
Discovery of a novel BTK inhibitor S-016 and identification of a new strategy for the treatment of lymphomas including BTK inhibitor-resistant lymphomas
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Song, Pei-ran
;
Wan, Zhi-peng
;
Huang, Ge-ge
;
Song, Zi-lan
;
Zhang, Tao
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2024/07/12
diffuse large B-cell lymphoma
BTK inhibitors
drug resistance
BTK C481F
BTK A428D
SYHA1813
Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23
作者:
Li, Xuemei
;
Wang, Peipei
;
Wang, Chang
;
Jin, Tingting
;
Xu, Ran
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11
作者:
Wang, Han-lin
;
Li, Jia-nan
;
Kan, Wei-juan
;
Xu, Gao-ya
;
Luo, Guang-hao
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/10/17
acute myeloid leukemia
cytarabine
daunorubicin
idarubicin
drug resistant
multi-omics
autophagy
chloroquine phosphate
Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 115034
作者:
Song, Shukai
;
Tang, Haotian
;
Ran, Ting
;
Fang, Feng
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/27
SyntaLinker
Generative modelling
TBK1 inhibitor
pyrrolo[2
3-d]pyrimidine
Structure-activity relationship
Genome size variation and polyploidy prevalence in the genus Eragrostis are associated with the global dispersal in arid area
期刊论文
OAI收割
FRONTIERS IN PLANT SCIENCE, 2023, 卷号: 14, 页码: 1066925
作者:
Hutang,Ge-Ran
;
Tong,Yan
;
Zhu,Xun-Ge
;
Gao,Li-Zhi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/05/09
genome size
phylogeny
Eragrostis
adaptation
environmental factors
GRASS SUBFAMILY CHLORIDOIDEAE
NUCLEAR-DNA CONTENT
TEF ZUCC TROTTER
CHROMOSOME-NUMBERS
PHYLOGENETIC SIGNAL
NICHE CONSERVATISM
MOLECULAR PHYLOGENY
DROUGHT TOLERANCE
MODEL SELECTION
SOUTH-AFRICAN
Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
作者:
Yan,Ying
;
Ran,Xiaoqian
;
Wang,Dan
;
Zhang,Xiong
;
Peng,Mingyou
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/07/25
UBIQUITIN-PROTEASOME SYSTEM
ALZHEIMERS-DISEASE
CONSTITUENTS
LIMONOIDS
TFEB
NEURODEGENERATION
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway
期刊论文
OAI收割
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
作者:
Ran,Xiaoqian
;
Lu,Qing-Yun
;
Li,Ying-Yao
;
Pu,Xue-Xue
;
Guo,Yarong
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/07/30
Euphorbia peplus L
Euphorbiaceae
Ent-abietane diterpenoid
Euphejolkinolide A
Autophagy-lysosomal pathway
ALZHEIMERS-DISEASE
TAU PATHOLOGY
NEURODEGENERATION
DITERPENOIDS
INHIBITION
MECHANISMS
APOPTOSIS
CELASTROL
PROTEIN
SYSTEM
The route to a 200 MHz, all-PM femtosecond Yb-doped fiber laser with a high output coupling ratio
期刊论文
OAI收割
APPLIED OPTICS, 2022, 卷号: 61, 期号: 28, 页码: 8475-8483
作者:
Zhang, Zhao
;
Zhang, Tong
;
Lv, Zhiguo
;
Zhang, Ting
;
Cheng, Haihao
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/10/28