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浏览/检索结果: 共209条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Structural Optimization of Next-Generation TRK Inhibitors against Acquired Drug Resistance Mutations for the Treatment of Solid Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 11, 页码: 11484-11501 作者:  Xu, Zichao;  Liu, Yueling;  Wang, Peng;  Peng, Xia;  Cheng, Jiawei   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/08/20 Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth 期刊论文  OAI收割 MOLECULES, 2025, 卷号: 30, 期号: 10, 页码: 22 作者:  Peng, Xia;  Yu, Siqi;  Xu, Lin;  Wang, Qinghua;  Yang, Lin   |  收藏  |  浏览/下载：16/0  |  提交时间：2025/07/25 pseudolaric acid B  amide derivatives  tumor-associated macrophages  anti-tumor  repolarization   Residue-Selective Inhibitors Discovery via Covalent DNA-Encoded Chemical Libraries with Diverse Warheads 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 18, 页码: 15469-15481 作者:  Wu, Xinyuan;  Pan, Jiayi;  Fan, Rufeng;  Zhang, Yiwei;  Wang, Chao   |  收藏  |  浏览/下载：25/0  |  提交时间：2025/06/23 Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 16 作者:  An, Yuxiang;  Peng, Xia;  Wang, Tianchen;  Liu, Kaiyuan;  Feng, Dazhi   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/12/25 inhibitor  pharmacokinetic study  pyridazin-4-one  receptor-interacting protein kinase 1  selectivity   Transcriptomic decoding of regional cortical vulnerability to major depressive disorder 期刊论文  OAI收割 COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12 作者:  Zhu, Jiajia;  Chen, Xiao;  Lu, Bin;  Li, Xue-Ying;  Wang, Zi-Han   |  收藏  |  浏览/下载：47/0  |  提交时间：2024/09/10 Remodeling tumor-associated macrophage for anti-cancer effects by rational design of irreversible inhibition of mitogen-activated protein kinase-activated protein kinase 2 期刊论文  OAI收割 MEDCOMM, 2024, 卷号: 5, 期号: 7, 页码: e634 作者:  Wang, Danyi;  Sun, Deqiao;  Wang, Xiaoyan;  Peng, Xia;  Ji, Yinchun   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/06/04 anti-tumor  irreversible inhibitor  kinase  macrophagemitogen-activated protein kinase-activated protein kinase 2 (MK2)   Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183 作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie   |  收藏  |  浏览/下载：46/0  |  提交时间：2024/02/27 Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：41/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13 作者:  Zhou, Ji;  Zhang, Xu-Chao;  Xue, Shan;  Dai, Mengdi;  Wang, Yueliang   |  收藏  |  浏览/下载：38/0  |  提交时间：2023/10/17 Laeviganoids A-T, ent-Clerodane-Type Diterpenoids from Croton laevigatus 期刊论文  OAI收割 JOURNAL OF NATURAL PRODUCTS, 2023, 页码: 15 作者:  Wang, Cheng-Lei;  Dai, Yang;  Zhu, Qiong;  Peng, Xia;  Liu, Quan-Fang   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/10/17