机构

• 上海药物研究所 [50]
• 合肥物质科学研究院 [26]
• 中国科学院大学 [7]
• 上海有机化学研究所 [3]
• 昆明动物研究所 [3]
• 大连化学物理研究所 [2]
• 更多

采集方式

• OAI收割 [90]
• iSwitch采集 [9]

内容类型

• 期刊论文 [94]
• 会议论文 [4]
• 学位论文 [1]

发表日期

• 2022 [3]
• 2021 [4]
• 2020 [3]
• 2019 [5]
• 2018 [10]
• 2017 [26]
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学科主题

• 物理化学 [2]
• Biochemist... [1]
• Cell Biolo... [1]
• Electroche... [1]
• 分析化学 [1]
• 氟化学 [1]
• 更多

筛选

浏览/检索结果: 共99条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of toxoflavin,a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 234 作者:  Liu Changmei;  Nie Litong;  Jiang Haini;  Xu Lei;  Zhang Kunzhi   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/05/22 endoplasmic reticulum stress  toxoflavin  reactive oxygen species  IRE1α  XBP1   DCZ19931, a novel multi-targeting kinase inhibitor, inhibits ocular neovascularization 期刊论文  OAI收割 SCIENTIFIC REPORTS, 2022, 卷号: 12, 期号: 1, 页码: 15 作者:  Zhang, Huiying;  Li, Bo;  Ding, Jingjuan;  Ye, Rong;  Xu, Zhijian   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/17 Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 233, 页码: 13 作者:  Tang, Qidong;  Peng, Ting;  Hu, Jie;  Zhang, Tao;  Chen, Pengqin   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/08/16 Reversible  irreversible pan-HER inhibitor  Quinazolin-4-amine derivatives  Anti-tumor  Structure-activity relationship   CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022 作者:  Cao, Jiang-yan;  Qi, Shuang;  Wu, Hong;  Wang, Ao-li;  Liu, Qing-wang   |  收藏  |  浏览/下载：53/0  |  提交时间：2022/03/28 HER2  breast cancers  gastric cancers  irreversible inhibitor  drug resistance   Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2021, 页码: 12 作者:  Guan, Xiang-Na;  Zhang, Tao;  Yang, Teng;  Dong, Ze;  Yang, Song   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/12/16 Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10 作者:  Meng, Jian;  Zhang, Hua;  Bao, Jing-jing;  Chen, Zhen-dong;  Liu, Xiao-yun   |  收藏  |  浏览/下载：69/0  |  提交时间：2021/06/11 metabolism  mass balance  distribution  covalent binding  furmonertinib   Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10 作者:  Meng, Jian;  Zhang, Hua;  Bao, Jing-jing;  Chen, Zhen-dong;  Liu, Xiao-yun   |  收藏  |  浏览/下载：61/0  |  提交时间：2021/06/11 metabolism  mass balance  distribution  covalent binding  furmonertinib   Effects of rifampicin on the pharmacokinetics of alflutinib, a selective third-generation EGFR kinase inhibitor, and its metabolite AST5902 in healthy volunteers 期刊论文  OAI收割 INVESTIGATIONAL NEW DRUGS, 2021, 页码: 8 作者:  Zhu, Yun-ting;  Zhang, Yi-fan;  Jiang, Jin-fang;  Yang, Yong;  Guo, Li-xia   |  收藏  |  浏览/下载：37/0  |  提交时间：2021/05/24 Alflutinib  Rifampicin  CYP3A4  AST5902  Drug-drug interaction   DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun   |  收藏  |  浏览/下载：66/0  |  提交时间：2021/05/24 receptor tyrosine kinase  FGFR inhibitor  DW14383  antitumor activity   Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12 作者:  Zheng, Yuan-dong;  Zhang, Hua;  Zhan, Yan;  Bian, Yi-cong;  Ma, Sheng   |  收藏  |  浏览/下载：29/0  |  提交时间：2021/05/24 vicagrel  [C-14]vicagrel  vicagrel pharmacokinetics  vicagrel metabolism  mass balance  P2Y(12) receptor inhibitor