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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [65]
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Design, synthesis, and biological profiling of novel aryl-spirocyclic diamine derivatives with potential antidepressant-like properties
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 301, 页码: 23
作者:
Zheng, Jiefang
;
Tian, Yaxin
;
Cheng, Jiaxin
;
Hu, Zhengtao
;
Zhang, Junchi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/12/04
Antidepressants
Multimodal monoaminergic compounds
Triple monoamine reuptake inhibitors
5-HT 3A R antagonist
Aryl-spirocyclic diamine derivatives
Soluble epoxide hydrolase deficiency rescues heart failure with preserved ejection fraction by targeting cytochrome P450 2E1
期刊论文
OAI收割
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2026, 卷号: 210, 页码: 98-108
作者:
Zhang, Min
;
Chen, Chen
;
Liu, Xinxing
;
Zhou, Zhou
;
Li, Gen
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2026/01/28
Soluble epoxide hydrolase
Desuccinylation
Epoxyeicosatrienoic acids
Heart failure with preserved ejection fraction
Oral VV261 administration protects mice from lethal Crimean-Congo hemorrhagic fever virus challenge
期刊论文
OAI收割
JOURNAL OF VIROLOGY, 2025, 页码: 5
作者:
Wang, Xi
;
Xu, Huan
;
Li, Liushuai
;
Wu, Fan
;
Li, Jiang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2026/01/28
Crimean-Congo hemorrhagic fever virus
nucleoside analog
VV261
oral administration
Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:
Zheng, Fuqiang
;
Hu, Zhengtao
;
Chen, Hai
;
Cheng, Jiaxin
;
Hou, Qiongqiong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2025/06/23
Heterocycle-fused phenylcyclohexylamines
Multi-target antagonists
NMDAR
Monoamine transporter
Antidepressants
Design and Development of a Novel Oral 4′-Fluorouridine Double Prodrug VV261 against SFTSV
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 9, 页码: 9811-9826
作者:
Cheng, Yong
;
Zheng, Wei
;
Dong, Xinru
;
Sun, Tengxiao
;
Xu, Mengwei
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2025/06/23
Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 113, 页码: 5
作者:
Lu, Jie
;
Cheng, Yan
;
Zhang, Yumin
;
Wang, Yi
;
Xia, Bingqing
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2025/02/28
Bisbenzylisoquinoline alkaloid
Oxyacanthine derivatives
SARS-CoV-2
Modular Combinatorial Development of Crystal-Glass Nano-Heterostructured Copper Alloys with Ultrahigh Strength and Large Deformability
期刊论文
OAI收割
ADVANCED FUNCTIONAL MATERIALS, 2024, 页码: 9
作者:
Zhou HB(周红波)
;
Yuan, Fusen
;
Huang, Yao
;
Wang, Yutian
;
Bo, Zhenxing
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2024/11/01
amorphous/crystalline materials
combinatorial method
heterostructure
high strength
large deformability
The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia
期刊论文
OAI收割
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2024, 卷号: 242, 页码: 13
作者:
Cheng, Jiaxin
;
Wu, Chunhui
;
Wang, Yu
;
Wang, Zhen
;
He, Yang
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2024/09/24
TPN672MA
5-HT 1A receptor agonist
D 2 /D 3 receptor partial agonist
5-HT 2A receptor antagonist
Antidepressant-like
Mechanism
Impurity study of tecovirimat
期刊论文
OAI收割
HELIYON, 2024, 卷号: 10, 期号: 9, 页码: 12
作者:
Bonku, Emmanuel Mintah
;
Qin, Hongjian
;
Odilov, Abdullajon
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2024/08/20
Tecovirimat
Genotoxic impurities
Process development
International Conference on Harmonization
(ICH)
Quality control
Combination of miR159 Mimics and Irinotecan Utilizing Lipid Nanoparticles for Enhanced Treatment of Colorectal Cancer
期刊论文
OAI收割
PHARMACEUTICS, 2024, 卷号: 16, 期号: 4, 页码: 18
作者:
Yang, Rulei
;
Liu, Yiran
;
Yang, Ning
;
Zhang, Tian
;
Hou, Jiazhen
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2024/05/31
colorectal cancer
plant-derived miR159
irinotecan
lipid nanoparticle