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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [11]
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OAI收割 [42]
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期刊论文 [40]
会议论文 [2]
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Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 15
作者:
Tang, Siyuan
;
Hu, Shuyang
;
Feng, Lijing
;
Kong, Linghui
;
Gui, Jiangwen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/27
N-Cyclopropylmethyl-nornepenthones
Structure-activity relationship
MOR antagonist
KOR agonist
Substance use disorder
Fracture mechanics of bi-material lattice metamaterials
期刊论文
OAI收割
JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS, 2024, 卷号: 192, 页码: 19
作者:
Song, Zhaoqiang
;
Wu, Kaijin
;
Wang, Zewen
;
He, Linghui
;
Ni Y(倪勇)
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/10/21
Bi-material lattice metamaterials
Fracture energy
Toughening mechanism
Stretch-bend synergism
Additive manufacturing
Discovery of an Ortho-Substituted
N
-Cyclopropylmethyl-7α-phenyl-6,14-
endo
ethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 9, 页码: 7112-7129
作者:
Li, Zixiang
;
Ye, Rufeng
;
He, Qian
;
Lu, Jiashuo
;
Sun, Yanting
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/06/27
Spatiotemporal Changes and the Prediction of Drought Characteristics in a Major Grain-Producing Area of China
期刊论文
OAI收割
SUSTAINABILITY, 2023, 卷号: 15, 期号: 22, 页码: 19
作者:
Guo, Linghui
;
Luo, Yuanyuan
;
Li, Yao
;
Wang, Tianping
;
Gao, Jiangbo
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/01/02
cropland exposure
drought event characteristics
drought prediction
Henan Province
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Offline Pre-trained Multi-agent Decision Transformer
期刊论文
OAI收割
Machine Intelligence Research, 2023, 卷号: 20, 期号: 2, 页码: 233-248
作者:
Linghui Meng
;
Muning Wen
;
Chenyang Le
;
Xiyun Li
;
Dengpeng Xing
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/23
Pre-training model
multi-agent reinforcement learning (MARL)
decision making
transformer
offline reinforcement learning
SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Kong, Linghui
;
Shu, Xuelian
;
Tang, Siyuan
;
Ye, Rongrong
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2022/08/30
GCS: Graph-Based Coordination Strategy for Multi-Agent Reinforcement Learning
会议论文
OAI收割
Online, 2022-5
作者:
Jingqing Ruan
;
Yali Du
;
Xuantang Xiong
;
Dengpeng Xing
;
Dengpeng Xing
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/09/10
Meteorological Influences on Spatiotemporal Variation of PM2.5 Concentrations in Atmospheric Pollution Transmission Channel Cities of the Beijing-Tianjin-Hebei Region, China
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2022, 卷号: 19, 期号: 3, 页码: 18
作者:
Wang, Suxian
;
Gao, Jiangbo
;
Guo, Linghui
;
Nie, Xiaojun
;
Xiao, Xiangming
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/09/21
PM2.5 concentration
spatiotemporal patterns
meteorological factors
"2+26" cities
Beijing-Tianjin-Hebei region
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:
He, Qian
;
Wei, Yuanyuan
;
Liu, Xiao
;
Ye, Rongrong
;
Kong, Linghui
  |  
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/11/04