中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [97]
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期刊论文 [197]
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The regulation of social factors on anxiety and microglial activity in nucleus accumbens of adolescent male mice: Influence of social interaction strategy
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2024, 卷号: 352, 页码: 525-535
作者:
Zhao, Mingyue
;
Xu, Xueping
;
Xu, Hang
;
Yang, Shuming
;
Li, Man
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/27
Adolescence
Physical and emotional stress
Social support
Social interaction strategies
Microglia
Nucleus Accumbens
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:
Xie, Xiong
;
Lan, Qiaoshuai
;
Zhao, Jinyi
;
Zhang, Sulin
;
Liu, Lu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
DNA-PK-Mediated Cytoplasmic DNA Sensing Stimulates Glycolysis to Promote Lung Squamous Cell Carcinoma Malignancy and Chemoresistance
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 5, 页码: 688-702
作者:
Wang, Hui
;
Zhang, Yanyang
;
Tian, Yu
;
Yang, Wanlin
;
Wang, Yan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Effect of bias voltage on the erosion performance of TiAlSiN coatings on TC6 substrate by high power impulse magnetron sputtering
期刊论文
OAI收割
SURFACE & COATINGS TECHNOLOGY, 2024, 卷号: 477, 页码: 20
作者:
Li, Hua
;
Li, Liuhe
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/26
Erosion
TiAlSiN
Bias voltage
HiPIMS
Failure mechanism
Targeting JMJD1C to selectively disrupt tumor T
reg
cell fitness enhances antitumor immunity
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2024, 页码: 32
作者:
Long, Xuehui
;
Zhang, Sulin
;
Wang, Yuliang
;
Chen, Jingjing
;
Lu, Yanlai
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/25
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1
H
)-one Analogues as Potent TRK Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:
Xu, Zichao
;
Peng, Xia
;
Zhang, Renjie
;
Ji, Yinchun
;
You, Mengke
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/02/27
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRAS
G12D
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Gu, Yuejiao
;
Ge, Zhiming
;
Tao, Zhaofan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
KinomeMETA: meta-learning enhanced kinome-wide polypharmacology profiling
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 25, 期号: 1, 页码: 15
作者:
Ren, Qun
;
Qu, Ning
;
Sun, Jingjing
;
Zhou, Jingyi
;
Liu, Jin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
kinome profiling
kinase inhibitors
polypharmacology
deep learning
meta-learning
Targeting ST8SIA6-AS1 counteracts KRAS
G12C
inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:
Wang, Yafang
;
Yao, Mingyue
;
Li, Cheng
;
Yang, Kexin
;
Qin, Xiaolong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
KRAS(G12C)
c-Myc
PLK1
LncRNA
ST8SIA6-AS1
Drug resistance
Precise measurement method of carrier motion state in microgravity environment
期刊论文
OAI收割
MEASUREMENT, 2023, 卷号: 222, 页码: 17
作者:
Liu, Mingyue
;
Zhu, Huizhong
;
Xu, Xinchao
;
Ma, Youqing
;
Zhang, Shuo
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/11/28
Multi-camera calibration
Stereo vision
Extraction of homonymous points
Random Sample Consensus (RANSAC)
Carrier motion state