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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
深圳先进技术研究院 [2]
上海光学精密机械研究... [2]
金属研究所 [1]
中国科学院大学 [1]
采集方式
OAI收割 [16]
iSwitch采集 [1]
内容类型
期刊论文 [17]
发表日期
2023 [1]
2022 [1]
2020 [1]
2019 [4]
2018 [2]
2017 [4]
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学科主题
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Phase Evolution and Glass Formation in an Fe-Based Alloy
期刊论文
OAI收割
ACTA METALLURGICA SINICA-ENGLISH LETTERS, 2023, 页码: 9
作者:
Huang, Ping
;
Shi, Yutong
;
Zhang, Wei
;
Zhang, Suode
;
Ren, Yinglei
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/07
Bulk metallic glass
Phase evolution
Crystallization kinetics
Cooling rate
F-18-FDG PET as an imaging biomarker for the response to FGFR-targeted therapy of cancer cells via FGFR-initiated mTOR/HK2 axis
期刊论文
OAI收割
THERANOSTICS, 2022, 卷号: 12, 期号: 14, 页码: 6395-6408
作者:
Jiang, Yuchen
;
Zeng, Qinghe
;
Jiang, Qinghui
;
Peng, Xia
;
Gao, Jing
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/12/13
F-18-FDG
FGFR
Therapeutic Response
PET/CT
mTOR/HK2
Design, Synthesis, and Biological Evaluation of HSP90 Inhibitor-SN38 Conjugates for Targeted Drug Accumulation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 10, 页码: 5421-5441
作者:
Zhu, Shulei
;
Shen, Qianqian
;
Gao, Yinglei
;
Wang, Lei
;
Fang, Yanfen
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and and in vivo study
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 351-368
作者:
Wei, Peng
;
Liu, Bo
;
Wang, Ruifeng
;
Gao, Yinglei
;
Li, Lanlan
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/07/01
Fibroblast growth factor
Tyrosine kinase receptor
Structure-based
Crystallography
Selectivity
Hybrid
5-Hydrosulfonyl-5H- pyrrolo[2.3-b]pyrazine
Inhibitor
Simultaneous inhibition of PI3K alpha and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-+
作者:
Wang, Yuxiang
;
Li, Xian
;
Liu, Xueling
;
Chen, Yi
;
Yang, Chunhao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
PI3K alpha
CDK4/6
KRAS
NSCLC
CYH33
Simultaneous inhibition of PI3Kα and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-83
作者:
Wang, Yuxiang
;
Li, Xian
;
Liu, Xueling
;
Chen, Yi
;
Yang, Chunhao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/21
PI3K alpha
CDK4/6
KRAS
NSCLC
CYH33
Simultaneous inhibition of PI3Kα and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer
期刊论文
OAI收割
Cancer Biology and Medicine, 2019, 卷号: 16, 期号: 1, 页码: 66
作者:
Wang Yuxiang
;
Li Xian
;
Liu Xueling
;
Chen Yi
;
Yang Chunhao
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/12/24
PI3Kα
CDK4/6
KRAS
NSCLC
CYH33
Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma
期刊论文
OAI收割
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689
作者:
Wang, Qi
;
Dai, Yang
;
Ji, Yinchun
;
Shi, Huanyu
;
Guo, Zuhao
  |  
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2019/01/08
Design, synthesis, and characterization of Schiffbase bond-linked pH-responsive doxorubicin prodrug based on functionalized mPEG-PCL for targeted cancer therapy
期刊论文
OAI收割
Polymers, 2018, 卷号: 10, 期号: 10
作者:
Zhai, Yinglei
;
Zhou, Xing
;
Zhang, Zhiqiang
;
Zhang, Lei
;
Wang, Dianyu
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531
作者:
Chen, Wenhua
;
Guo, Ne
;
Qi, Minghui
;
Dai, Haiying
;
Hong, Minghuang
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Antitumor drug
BRCA1/2
PARP inhibitors
Molecular docking