中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
期刊论文
OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:
Bian, Yi-cong
;
Meng, Jian
;
Hu, Tao
;
Ma, Sheng
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
HSK7653
long-acting dipeptidyl peptidase-4 inhibitor
mass balance
metabolism
pharmacokinetics
radiolabelled
Attribution of Terrestrial Near-Surface Wind Speed Changes Across China at a Centennial Scale
期刊论文
OAI收割
GEOPHYSICAL RESEARCH LETTERS, 2024, 卷号: 51, 期号: 7, 页码: 10
作者:
Zha, Jinlin
;
Chuan, Ting
;
Wu, Jian
;
Zhao, Deming
;
Luo, Meng
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/05/06
near-surface wind speed
regional climate model
centennial scale
causality
detection and attribution
The development of logic gate-based fluorescent probes that respond to intracellular hydrogen peroxide and pH in tandem
期刊论文
OAI收割
TALANTA, 2024, 卷号: 270, 页码: 8
作者:
Han, Hai-Hao
;
Liu, Meng-Jiao
;
Zhang, Weijian
;
Sun, Lu-Lu
;
Ma, Xiuhua
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/19
Reactive oxygen species (ROS)
pH
Logic gate
Fluorescent probe
Cell imaging
Regioselective Deacetylation of Peracetylated Deoxy-
C
-glycopyranosides by Boron Trichloride (BCl
3
)
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2024, 页码: 16
作者:
Chen, Shuangyuan
;
Wei, Feifei
;
Cheng, Xinqiang
;
Luo, Ying
;
Meng, Fancui
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Quantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting the PDGFRβ/PI3K/AKT pathway
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Meng, Qian
;
Zhu, Hongwen
;
Li, Yuanyuan
;
Peng, Xiaotian
;
Wang, Tianming
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Yinchenzhufu decoction
proteomics
cholestasis
liver fibrosis
PDGFR beta/PI3K/AKT
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2024, 卷号: 72, 期号: 8, 页码: 4142-4154
作者:
Yang, Yu-Hong
;
Chen, Chen
;
Zheng, Yan
;
Wu, Zi-Jian
;
Zhou, Meng-Qing
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/04/07
fucoxanthin
colitis
intestinal barrier function
anti-inflammation
antioxidation
gut microbiota
Influence of loneliness burden on cardio-cerebral vascular disease among the Chinese older adult: a national cohort study
期刊论文
OAI收割
FRONTIERS IN PUBLIC HEALTH, 2024, 卷号: 12, 页码: 9
作者:
Wu, Dishan
;
Hu, Xing
;
Meng, Lingbing
;
Li, Jianyi
;
Xu, Jiapei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/04/01
loneliness
cardio-cerebral vascular diseases
cumulative burden
older adult
longitudinal change
DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser
56
to diminish pancreatic β cell function upon overnutrition
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16
作者:
Lu, Yuting
;
Xu, Junyu
;
Li, Yufeng
;
Wang, Ruoran
;
Dai, Chengqiu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/03/13
Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:
Chen, Xuetao
;
Wu, Tingting
;
Du, Zhiyan
;
Kang, Wenjing
;
Xu, Rujun
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/02/27
BET
BD1
Bromodomain
Brain-permeable
Multiple sclerosis
Sub-Bin Delayed High-Range Accuracy Photon-Counting 3D Imaging
期刊论文
OAI收割
PHOTONICS, 2024, 卷号: 11, 期号: 2
作者:
Yin, Hao-Meng
;
Zhao, Hui
;
Yang, Ming-Yang
;
Liu, Yong-An
;
Sheng, Li-Zhi
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/12
single-photon imaging
3D imaging
range accuracy
quantisation error