中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
高能物理研究所 [314]
近代物理研究所 [144]
上海药物研究所 [118]
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期刊论文 [1608]
会议论文 [27]
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Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
Soil moisture and precipitation dominate the response and recovery times of ecosystems from different types of flash drought in the Yangtze River Basin
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2024, 卷号: 358, 页码: 16
作者:
Hu, Chen
;
She, Dunxian
;
Wang, Gangsheng
;
Zhang, Liping
;
Jing, Zhaoxia
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/11/28
Flash droughts
Response time
Recovery time
Flash drought types
Diverge vegetations
Ecological restoration enhances dryland carbon stock by reducing surface soil carbon loss due to wind erosion
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 46, 页码: 10
作者:
Song, Jian
;
Wan, Shiqiang
;
Zhang, Kesheng
;
Hong, Songbai
;
Xia, Jianyang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/02/06
carbon neutrality
climate solutions
plant productivity
soil carbon
soil erosion
An unusual winter bloom of dinoflagellates with notable damage to kelp cultivation around Shandong peninsula, China
期刊论文
OAI收割
MARINE ENVIRONMENTAL RESEARCH, 2024, 卷号: 201, 页码: 9
作者:
Geng, Hui-Xia
;
Kong, Fan-Zhou
;
Wang, Jin-Xiu
;
Zhang, Qing-Chun
;
Li, Fang
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/12/20
Harmful algal bloom
dinoflagellate
Eutrophication
Extreme precipitation
Aberrant copper metabolism and hepatic inflammation cause neurological manifestations in a mouse model of Wilson's disease
期刊论文
OAI收割
JOURNAL OF NEUROINFLAMMATION, 2024, 卷号: 21
作者:
Dong, Jianjian
;
Xiang, Guanghai
;
Xia, Xiaoxue
;
Xu, Lewen
;
Wen, Peihua
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/11/20
Wilson's disease
ATP7B gene
R778L point mutation
Hepatic inflammation
Neurological manifestations
CRISPR/Cas9
Chemoproteomics of Marine Natural Product Naamidine J Unveils CSE1L as a Therapeutic Target in Acute Lung Injury
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 14
作者:
Gao, Cheng-Long
;
Song, Jin-Qian
;
Yang, Ze-Nan
;
Wang, Haojie
;
Wu, Xin-Yuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/11/05
Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:
Li, Hongrui
;
Liu, Ben-Jin
;
Xu, Jiahao
;
Song, Shan-Shan
;
Ba, Ruixian
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/08/22
USP1 inhibitor
Structure -activity relationships
Olaparib-resistant cell
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/09/10
FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15
作者:
Wen, Ying-quan
;
Zou, Zi-yuan
;
Zhao, Guan-guan
;
Zhang, Meng-jiao
;
Zhang, Yong-xin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/22
MASLD/MASH
FXR
transcriptome
gut-liver axis
agonist
The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 716, 页码: 12
作者:
Xuan, Yi-Fei
;
Lu, Shan
;
Ou, Ying-Jie
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/07/12
MAT2A inhibitor
METTL3 inhibitor
m6A
Combination therapy
NSCLC