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Chinese Academy of Sciences Institutional Repositories Grid
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UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 237, 页码: 19
作者:
Wang, Li
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Bao, Xu-Bin
;
Tian, Chang-Qing
  |  
收藏
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浏览/下载:0/0
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提交时间:2025/06/23
UBE4B
BET inhibitors
Resistance
KLHL22
JAK2
The combination of BET and METTL3 inhibitors elicits synergistic antitumor effects in ovarian cancer cells
via
reducing SP1 and BCL-2 expression
期刊论文
OAI收割
LIFE SCIENCES, 2025, 卷号: 368, 页码: 14
作者:
Ou, Ying-Jie
;
Liu, Ben-Jin
;
Xuan, Yi-Fei
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
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浏览/下载:0/0
  |  
提交时间:2025/04/24
BET inhibitor
METTL3 inhibitor
Combination therapy
SP1
BCL-2
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
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收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
Modelling of thermo-mechanical coupling effects in rock masses using an enriched nodal-based continuous-discontinuous deformation analysis method
期刊论文
OAI收割
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 2025, 卷号: 433, 页码: 37
作者:
Xia, Yang
;
Yang, Yongtao
;
Zheng, Hong
;
Wang, Shuilin
  |  
收藏
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浏览/下载:0/0
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提交时间:2025/06/27
Nodal-based continuous-discontinuous deformation analysis method (NCDDAM)
Contact approach
Thermo-mechanical coupling
Thermal cracking
Failure of rock masses
Probabilistic assessment of the thermal performance of low-enthalpy geothermal system under impact of spatially correlated heterogeneity by using XGBoost algorithms
期刊论文
OAI收割
ENERGY, 2024, 卷号: 313, 页码: 18
作者:
Liao, Jianxing
;
Xie, Yachen
;
Zhao, Pengfei
;
Xia, Kaiwen
;
Xu, Bin
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/27
Thermal performance
Reservoir heterogeneity
XGBoost
SHAP
Probability of failure
Soil moisture and precipitation dominate the response and recovery times of ecosystems from different types of flash drought in the Yangtze River Basin
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2024, 卷号: 358, 页码: 16
作者:
Hu, Chen
;
She, Dunxian
;
Wang, Gangsheng
;
Zhang, Liping
;
Jing, Zhaoxia
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收藏
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浏览/下载:6/0
  |  
提交时间:2024/11/28
Flash droughts
Response time
Recovery time
Flash drought types
Diverge vegetations
Ecological restoration enhances dryland carbon stock by reducing surface soil carbon loss due to wind erosion
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 46, 页码: 10
作者:
Song, Jian
;
Wan, Shiqiang
;
Zhang, Kesheng
;
Hong, Songbai
;
Xia, Jianyang
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收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/02/06
carbon neutrality
climate solutions
plant productivity
soil carbon
soil erosion
An unusual winter bloom of dinoflagellates with notable damage to kelp cultivation around Shandong peninsula, China
期刊论文
OAI收割
MARINE ENVIRONMENTAL RESEARCH, 2024, 卷号: 201, 页码: 9
作者:
Geng, Hui-Xia
;
Kong, Fan-Zhou
;
Wang, Jin-Xiu
;
Zhang, Qing-Chun
;
Li, Fang
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收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/12/20
Harmful algal bloom
dinoflagellate
Eutrophication
Extreme precipitation
Aberrant copper metabolism and hepatic inflammation cause neurological manifestations in a mouse model of Wilson's disease
期刊论文
OAI收割
JOURNAL OF NEUROINFLAMMATION, 2024, 卷号: 21
作者:
Dong, Jianjian
;
Xiang, Guanghai
;
Xia, Xiaoxue
;
Xu, Lewen
;
Wen, Peihua
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/11/20
Wilson's disease
ATP7B gene
R778L point mutation
Hepatic inflammation
Neurological manifestations
CRISPR/Cas9
Chemoproteomics of Marine Natural Product Naamidine J Unveils CSE1L as a Therapeutic Target in Acute Lung Injury
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 14
作者:
Gao, Cheng-Long
;
Song, Jin-Qian
;
Yang, Ze-Nan
;
Wang, Haojie
;
Wu, Xin-Yuan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/05