中国科学院机构知识库网格
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Primary Amine-Based Photoclick Chemistry: From Concept to Diverse Applications in Chemical Biology and Medicinal Chemistry
期刊论文
OAI收割
ACCOUNTS OF CHEMICAL RESEARCH, 2025, 卷号: 58, 期号: 13, 页码: 1963-1981
作者:
Hu, Hao
;
Nie, Hui-Jun
;
Chen, Xiao-Hua
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/08/20
Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 15
作者:
Xu, Yali
;
Hu, Hao
;
Ran, Yu
;
Zhao, Wensi
;
Guo, An-Di
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Chemoproteomics
Molecular glue degraders
Photo-crosslinking
Protein-protein interactions
Targeted protein degradation
Risk assessment of CYP3A induction by ginsenoside's metabolites from oral Panax notoginseng (sanqi) extract
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 349, 页码: 11
作者:
Deng, Yang
;
Du, Jing
;
He, Xin
;
Dong, Yan-Xi
;
Wang, Xiao-Lei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Panax notoginseng
Ginsenoside
Intestinal microbiota
CYP3A induction
Drug interaction
Supermassive Black Holes with High Accretion Rates in Active Galactic Nuclei. XIV. Long-duration High-cadence Reverberation Mapping Results for 11 PG Quasars
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 2025, 卷号: 278, 期号: 2
作者:
Hu, Chen
;
Yao, Zhu-Heng
;
Chen, Yong-Jie
;
Songsheng, Yu-Yang
;
Wang, Yi-Lin
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/06/23
Detection of an Orphan X-Ray Flare from a Blazar Candidate EP240709a with the Einstein Probe
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 984, 期号: 1
作者:
Liu, Mingjun
;
Zhang, Yijia
;
Wang, Yun
;
Xue, Rui
;
Buckley, David
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2025/05/05
Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 13
作者:
Xu, Yali
;
Zhao, Wensi
;
Nie, Hui-Jun
;
Wang, Jiamin
;
Fu, Jingjing
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/05/27
Chemoproteomics
Genetic code expansion
Molecular glue degrader
Photo-crosslinking
Targeted protein degradation
Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 653, 页码: 13
作者:
Sun, Ming-Dao
;
Lin, Qin
;
Ramezani, Jahandar
;
Liu, Jiang-Si
;
Lu, Zheng-An
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2025/04/03
Early Cretaceous
Aptian
CA-ID-TIMS geochronology
Astrochronology
Carbon isotope stratigraphy
Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 14
作者:
Chen, Yu-jun
;
Zhao, Yu
;
Yao, Ming-yue
;
Wang, Ya-fang
;
Ma, Ming
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2025/04/01
acute myeloid leukemia
FLT3
p300/CBP
quizartinib resistance
combination strategy
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2025/04/01
Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
Nie, Hui-Jun
;
Li, Ben-Fu
;
Sun, Jingya
;
Yuan, Yali
;
Zhang, Zhi-Gao
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9