中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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高能物理研究所 [433]
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浏览/检索结果:
共2634条,第1-10条
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
The Overview and Trial Observations of AIMS
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Deng, Yuanyong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/07/14
Sun: infrared
methods: observational
instrumentation: spectrographs
Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 15
作者:
Xu, Yali
;
Hu, Hao
;
Ran, Yu
;
Zhao, Wensi
;
Guo, An-Di
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Chemoproteomics
Molecular glue degraders
Photo-crosslinking
Protein-protein interactions
Targeted protein degradation
Advancing active compound discovery for novel drug targets: insights from AI-driven approaches
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12
作者:
Wang, Xing-you
;
Chen, Yang
;
Li, Yu-fan
;
Wei, Chao-yang
;
Liu, Meng-ya
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
AI-driven drug discovery
novel drug targets
molecular design
ligand exploration
phenotypic drug discovery
undruggable targets
Triconnarins A-D: Four Secophragmalin-Type Limonoids from the Twigs and Leaves of
Trichilia connaroides
期刊论文
OAI收割
ORGANIC LETTERS, 2025, 卷号: 27, 期号: 25, 页码: 6772-6776
作者:
Xu, Jia-Xin
;
Zhao, Hai-Yang
;
Li, Xiao-Zhou
;
Li, Zhi-Ying
;
Shen, Tao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Numerical investigation on helium pressurization behavior of cryogenic propellant in microgravity
期刊论文
OAI收割
APPLIED THERMAL ENGINEERING, 2025, 卷号: 269
作者:
Guo, Songyuan
;
Jiang, Zan
;
Li, Jianqiang
;
Xu, Pengli
;
Zhuan, Rui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/07/21
Cryogenic propellant
Microgravity
Pressurization
Species transfer
Detection of an Orphan X-Ray Flare from a Blazar Candidate EP240709a with the Einstein Probe
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 984, 期号: 1
作者:
Liu, Mingjun
;
Zhang, Yijia
;
Wang, Yun
;
Xue, Rui
;
Buckley, David
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/05/05
Substrate recognition and cleavage mechanism of the monkeypox virus core protease
期刊论文
OAI收割
NATURE, 2025, 页码: 29
作者:
Gao, Yan
;
Xie, Xiong
;
Zhang, Xiaoyu
;
Cao, Junyuan
;
Lan, Weiqi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Late spring-early summer drought and soil properties jointly modulate two pine species' decline and climatic sensitivity in temperate Northern China
期刊论文
OAI收割
FOREST ECOSYSTEMS, 2025, 卷号: 12, 页码: 100273
作者:
Li, Yuheng
;
Fan, Zhaofei
;
Xu, Lihong
;
Zhang, Xiao
;
Shi, Zhongjie
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2025/02/24
Tree rings
Climate sensitivity
Growth decline
Global warming
Drought
Soil property