中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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期刊论文 [1018]
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Design and structural optimization of novel SOS1 inhibitors in KRAS-driven cancers
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 125, 页码: 8
作者:
Chen, Yating
;
Liu, Qiupei
;
Meng, Xianghui
;
Cao, Wenxu
;
Duo, Lihui
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
SOS1 inhibitor
KRAS mutation
SOS1-KRAS interaction
Resistance
Tracheal Targeted Nanogrid Delivery Systems of Dexamethasone Visualized by Single-Particle Tracing and Multiscale Pathological Mapping
期刊论文
OAI收割
ACS NANO, 2025, 卷号: 19, 期号: 25, 页码: 23414-23430
作者:
Cao, Zeying
;
Zhou, Shilin
;
Zhao, Yanli
;
Wu, Qian
;
Huang, Chenxi
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
three-dimensional pathology
nanogrid
ROS-scavenging
tracheal targeted
bronchitis
nano-bio-interactions
Development of Orally Bioavailable Octahydroindole-Based Peptidomimetic Derivative as a Broad-Spectrum Inhibitor against HCoV-OC43 and SARS-CoV-2
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 11, 页码: 10823-10844
作者:
Hu, Shulei
;
Zhang, Yumin
;
Wang, Chenchen
;
Li, Jian
;
Su, Haixia
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/07/25
Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism
期刊论文
OAI收割
CELL METABOLISM, 2025, 卷号: 37, 期号: 5, 页码: 32
作者:
Jiang, Jie
;
Gao, Yuqing
;
Wang, Jiang
;
Huang, Yan
;
Yang, Rong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Substrate recognition and cleavage mechanism of the monkeypox virus core protease
期刊论文
OAI收割
NATURE, 2025, 页码: 29
作者:
Gao, Yan
;
Xie, Xiong
;
Zhang, Xiaoyu
;
Cao, Junyuan
;
Lan, Weiqi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Mapping global yields of four major crops at 5-minute resolution from 1982 to 2015 using multi-source data and machine learning
期刊论文
OAI收割
SCIENTIFIC DATA, 2025, 卷号: 12, 期号: 1, 页码: 357
作者:
Cao, Juan
;
Zhang, Zhao
;
Luo, Xiangzhong
;
Luo, Yuchuan
;
Xu, Jialu
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/04/21
Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 20
作者:
Peng, Chang
;
Jiang, Haowen
;
Jing, Liya
;
Yang, Wenhua
;
Guan, Xiaotong
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2025/04/01
Glycyrrhizic acid and patchouli alcohol in Huoxiang Zhengqi attenuate intestinal inflammation and barrier injury via regulating endogenous corticosterone metabolism mediated by 11β-HSD1
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 338, 页码: 17
作者:
Wang, Yangyang
;
Sun, Chuying
;
Cao, Yutang
;
Jiao, Tingying
;
Wang, Kanglong
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/12/16
Huoxiang Zhengqi
Glycyrrhizic acid
Patchouli alcohol
Inflammation
Intestinal barrier injury
11 beta-hydroxysteroid dehydrogenase 1
Zexie-Baizhu Decoction ameliorates non-alcoholic fatty liver disease through gut-adipose tissue crosstalk
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 337, 页码: 14
作者:
Shi, Jingying
;
Liu, Yawen
;
Zhang, Zijia
;
Zhong, Xianchun
;
Cao, Yuhan
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2024/10/21
Zexie-Baizhu Decoction
Traditional Chinese medicine
Akkermansia muciniphila
Bile acids
Short chain fatty acid
Lipidomics
2-(1-Phenylvinyl)benzoic acid as a highly active leaving group for metal-free glycosylation
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2025, 页码: 7
作者:
Dai, Qi
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/04/01