中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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SRY-Box transcription factor 9 triggers YAP nuclear entry via direct interaction in tumors
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 13
作者:
Qian, Hui
;
Ding, Chen-Hong
;
Liu, Fang
;
Chen, Shi-Jie
;
Huang, Chen-Kai
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:
Xie, Xiong
;
Lan, Qiaoshuai
;
Zhao, Jinyi
;
Zhang, Sulin
;
Liu, Lu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 inhibitors: Research progress and prospects
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 13
作者:
Guan, Dezhong
;
Fang, Lincheng
;
Feng, Mingshun
;
Guo, Shi
;
Xie, Lingfeng
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
ENPP1 inhibitors
cGAS-STING pathway
2 ', 3 '-cGAMP
Tumor immunotherapy
A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy
期刊论文
OAI收割
CANCER COMMUNICATIONS, 2024, 页码: 5
作者:
Liu, Yingqiang
;
Tong, Linjiang
;
Zhang, Mengge
;
Zhang, Qi
;
Liu, Qiupei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/13
CFNet: Conditional filter learning with dynamic noise estimation for real image denoising
期刊论文
OAI收割
KNOWLEDGE-BASED SYSTEMS, 2024, 卷号: 284, 页码: 12
作者:
Zuo, Yifan
;
Yao, Wenhao
;
Zeng, Yifeng
;
Xie, Jiacheng
;
Fang, Yuming
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/03/26
Image denoising
Noise estimation
Conditional filter
Affine transform
Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12
作者:
Song, Zhaoxiang
;
Lu, Dan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/01/16
GPR35
IBD
Lodoxamide
Quantification of Long-Range Dependence in Hydroclimatic Time Series: A Method-Comparison Study
期刊论文
OAI收割
JOURNAL OF APPLIED METEOROLOGY AND CLIMATOLOGY, 2023, 卷号: 62, 期号: 12, 页码: 1921-1942
作者:
Niu, Jingyi
;
Xie, Ping
;
Sang, Yan-Fang
;
Zhang, Liping
;
Wu, Linqian
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/04
Regression analysis
Statistical techniques
Time series
Stochastic models
Climate variability
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
DRS: A deep reinforcement learning enhanced Kubernetes scheduler for microservice-based system
期刊论文
OAI收割
SOFTWARE-PRACTICE & EXPERIENCE, 2023, 页码: 25
作者:
Jian, Zhaolong
;
Xie, Xueshuo
;
Fang, Yaozheng
;
Jiang, Yibing
;
Lu, Ye
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/04
deep reinforcement learning
Kubernetes scheduler
microservice scheduling
resource awareness
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder