机构

• 上海药物研究所 [11]

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [11]

发表日期

• 2024 [4]
• 2023 [2]
• 2020 [1]
• 2019 [1]
• 2018 [1]
• 2016 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Single Amine or Guanidine Modification on Norvancomycin and Vancomycin to Overcome Multidrug-Resistance through Augmented Lipid II Binding and Increased Membrane Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20639-20663 作者:  Bian, Xiaolei;  Chen, Zhifu;  Li, Fang;  Xie, Yuanyuan;  Li, Yi   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/12/11 Discovery of Alkyl Conjugated Diene Diacids as Novel ACLY Inhibitors 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 11, 页码: 3476-3489 作者:  Cheng, Tingting;  Song, Gaolei;  Cheng, Long;  Wang, Fan;  Sun, Xinyu   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/02/28 metabolic diseases  ATP-citrate lyase (ACLY)  lipogenesis  ACLY inhibitors  dienyldicarboxylic acid   Simultaneous determination of BGT-002 and its acyl glucuronide metabolite ZM326E-M2 in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 243, 页码: 8 作者:  Zhu, Xueran;  Cui, Shumin;  Liu, Xinjing;  Zhang, Mei;  Xie, Zhifu   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/05/31 ATP-Citrate Lyase  BGT-002  Acyl glucuronide metabolite  Pseudo-MRM  LC-MS/MS  Pharmacokinetics   AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise 期刊论文  OAI收割 SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 6, 页码: 15 作者:  Xiao, Liwei;  Yin, Yujing;  Sun, Zongchao;  Liu, Jing;  Jia, Yuhuan   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/05/31 HIF-1 alpha inhibition in macrophages preserves acute liver failure by reducing IL-1 beta production 期刊论文  OAI收割 FASEB JOURNAL, 2023, 卷号: 37, 期号: 9, 页码: 12 作者:  Kong, Xiangrong;  Liu, Wei;  Zhang, Xinwen;  Zhou, Chendong;  Sun, Xinyu   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 acute liver failure  cell death  HIF-1 alpha inhibitor  interleukin-1 beta  macrophage   Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 2, 页码: 739-753 作者:  Xie, Zhifu;  Zhang, Mei;  Song, Qian;  Cheng, Long;  Zhang, Xinwen   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/03/27 Hypercholesterolemia  Atherosclerosis  Liver  ATP-Citrate lyase (ACLY)  Lipogenesis  Cholesterol efflux  ACLY inhibitor   The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling 期刊论文  OAI收割 CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10 作者:  Xie, Zhifu;  Jiang, Haowen;  Liu, Wei;  Zhang, Xinwen;  Chen, Dakai   |  收藏  |  浏览/下载：46/0  |  提交时间：2020/12/21 Mitochondrial Uncoupling Coordinated With PDH Activation Safely Ameliorates Hyperglycemia via Promoting Glucose Oxidation 期刊论文  OAI收割 DIABETES, 2019, 卷号: 68, 期号: 12, 页码: 2197-2209 作者:  Jiang, Haowen;  Jin, Jia;  Duan, Yanan;  Xie, Zhifu;  Li, Yufeng   |  收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01 AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue 期刊论文  OAI收割 FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9 作者:  Wu, Lingyan;  Zhang, Lina;  Li, Bohan;  Jiang, Haowen;  Duan, Yanan   |  收藏  |  浏览/下载：63/0  |  提交时间：2019/01/08 AMP-activated protein kinase  thermogenesis  energy metabolism  A-769662  white adipose browning  PGC-1 alpha   Discovery, synthesis, and structure-activity relationships of 20S-dammar-24-en-2 alpha,3 beta,12 beta,20-tetrol (GP) derivatives as a new class of AMPK alpha 2 beta 1 gamma 1 activators 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2688-2696 作者:  Dong, Chenhuan;  Xie, Zhifu;  Yu, Yanyan;  Li, Jia;  Liu, Junhua   |  收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 Gynostemma yixingense  Dammarane-type  AMPK  AMPK heterotrimer alpha 2 beta 1 gamma 1  Activators  Structure-activity relationships