中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Fluorescence-Coupled Ubiquitination Assay as a High-Throughput Screening Strategy for Novel Cereblon Degraders 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 10111-10127
作者:  
Deng, Yanan;  Yang, Shiling;  Xu, Hesong;  Ding, Xiyao;  Xu, Ying
  |  收藏  |  浏览/下载:1/0  |  提交时间:2025/06/23
Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17
作者:  
Hu, Linghao;  Xu, Hesong;  Xu, Ye;  Chen, Haowen;  Jiang, Hanrui
  |  收藏  |  浏览/下载:15/0  |  提交时间:2025/04/01
Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14
作者:  
Guo, Siqi;  Jia, Tongguan;  Xu, Xiaoming;  Yang, Feng;  Xiao, Senhao
  |  收藏  |  浏览/下载:34/0  |  提交时间:2023/04/10
Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties 期刊论文  OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555
作者:  
Li, Ennian;  Wang, Kai;  Zhang, Bei;  Guo, Siqi;  Xiao, Senhao
  |  收藏  |  浏览/下载:65/0  |  提交时间:2022/08/16