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UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 237, 页码: 19
作者:
Wang, Li
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Bao, Xu-Bin
;
Tian, Chang-Qing
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/23
UBE4B
BET inhibitors
Resistance
KLHL22
JAK2
Structural optimization and discovery of high effective isopropanolamine-based TPS1 inhibitors as promising broad-spectrum fungicide candidates
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 290, 页码: 17
作者:
Jiang, Zhiyang
;
Wang, Na
;
Chen, Jinxiu
;
Xu, Huan
;
Zhu, Wenya
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/05/27
Trehalose-6-phosphate synthase
Structural optimization
Isopropanolamine compounds
Inhibitors
Fungicide candidates
Fluorescence-Coupled Ubiquitination Assay as a High-Throughput Screening Strategy for Novel Cereblon Degraders
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 10111-10127
作者:
Deng, Yanan
;
Yang, Shiling
;
Xu, Hesong
;
Ding, Xiyao
;
Xu, Ying
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/23
The combination of BET and METTL3 inhibitors elicits synergistic antitumor effects in ovarian cancer cells
via
reducing SP1 and BCL-2 expression
期刊论文
OAI收割
LIFE SCIENCES, 2025, 卷号: 368, 页码: 14
作者:
Ou, Ying-Jie
;
Liu, Ben-Jin
;
Xuan, Yi-Fei
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
BET inhibitor
METTL3 inhibitor
Combination therapy
SP1
BCL-2
Microbiota-shaped neutrophil senescence regulates sexual dimorphism in bladder cancer
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2025, 卷号: 26, 期号: 5, 页码: 46
作者:
Zhu, Qingchen
;
Zhang, Guiheng
;
Cao, Ming
;
Huang, Huan
;
He, Dan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Proteogenomic characterization of non-functional clinically relevant subgroups
期刊论文
OAI收割
CANCER CELL, 2025, 卷号: 43, 期号: 4, 页码: 36
作者:
Ji, Shunrong
;
Cao, Lihua
;
Gao, Jing
;
Du, Yang
;
Ye, Zeng
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Urbanization-driven and intercity interaction-induced warming effects in the Beijing-Tianjin-Hebei urban agglomeration: A comparison of heatwave and non-heatwave scenarios
期刊论文
OAI收割
APPLIED GEOGRAPHY, 2025, 卷号: 177, 页码: 103561
作者:
Qiao, Zhi
;
Wei, Qikun
;
Gao, Huan
;
Liu, Luo
;
Xu, Xinliang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/21
Urban thermal environment
Heatwave
Urbanization
Interactive impact
WRF-UCM
Beijing-Tianjin-Hebei urban agglomeration
USP7 V517F mutation as a mechanism of inhibitor resistance
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 14
作者:
Miao, Yu-Ling
;
Fan, Fengying
;
Cheng, Yong-Jun
;
Jia, Li
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/05/27
A downscaling framework with WRF-UCM and LES/RANS models for urban microclimate simulation strategy: Validation through both measurement and mechanism model
期刊论文
OAI收割
BUILDING AND ENVIRONMENT, 2025, 卷号: 269, 页码: 13
作者:
Liu, Jiawen
;
Gao, Huan
;
Jia, Ruoyu
;
Wang, Ran
;
Han, Dongrui
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/03/03
Urban microclimate simulation
One-way downscaling method
WRF-UCM model
ENVI-met
PALM-4U
The two-resistance mechanism (TRM) model
Multisite modifications of arenes using ketones as removable handles enabled by Pd and norbornene cooperative catalysis
期刊论文
OAI收割
NATURE SYNTHESIS, 2025, 卷号: 4, 期号: 2
作者:
Tao, Kai-Liang
;
Wang, Xing
;
Liu, Huan
;
Chen, Wen-Qing
;
Sun, Yi
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/06/04