中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [45]
采集方式
OAI收割 [45]
内容类型
期刊论文 [45]
发表日期
2024 [1]
2023 [3]
2022 [3]
2021 [9]
2020 [4]
2019 [4]
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专题:上海药物研究所
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Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the assay of 12 substances in rat plasma and its application to rat pharmacokinetics of
Epimedium
and
Psoraleae Fructus
herb pair after oral administration
期刊论文
OAI收割
JOURNAL OF SEPARATION SCIENCE, 2024, 卷号: 47, 期号: 1, 页码: 17
作者:
Wang, Linwei
;
Yin, Xiaoying
;
Liu, Huan
;
Wang, Yangyang
;
Li, Zhixiong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/27
compatibility behaviors
Epimedium
LC-MS/MS
pharmacokinetics
Psoraleae Fructus
Proteasome inhibitors reduce CD73 expression partly
via
decreasing p-ERK in NSCLC cells
期刊论文
OAI收割
LIFE SCIENCES, 2023, 卷号: 332, 页码: 10
作者:
Su, Ai-Ling
;
Tian, Chang-Qing
;
Ou, Ying-Jie
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
CD73
Proteasome inhibitors
ERK
NSCLC
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
TRPV4 is not the molecular sensor for bacterial lipopolysaccharides-induced calcium signaling
期刊论文
OAI收割
CELLULAR IMMUNOLOGY, 2023, 卷号: 383, 页码: 8
作者:
Wang, Yuhui
;
Hao, Yanping
;
Jin, Jinhua
;
Yi, Zhihua
;
Liu, Yifei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
TRPV4
LPS
Calcium influx
Whole cell current
Pain
Inflammation
SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy
期刊论文
OAI收割
NEOPLASIA, 2022, 卷号: 32, 页码: 12
作者:
Zhou, Li-Na
;
Xiong, Chaodong
;
Cheng, Yong-Jun
;
Song, Shan-Shan
;
Bao, Xu-Bin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/04/10
SOMCL-19-133
NAE inhibitor
MLN4924
NEDD8
Oral administration
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 229, 页码: 22
作者:
Li, Xiaokang
;
Li, Jinwen
;
Huang, Yunyuan
;
Gong, Qi
;
Fu, Yan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/15
Alzheimer's disease
Depression
Comorbidity
Multi-target-directed ligands
Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma (vol 417, 128103, 2021)
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2022, 卷号: 428, 页码: 2
作者:
Geng, Huan
;
Zhou, Mengxue
;
Li, Bin
;
Liu, Liang
;
Yang, Xu
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/01/18
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Wang, Lin
;
Wu, Yan
;
Yao, Sheng
;
Ge, Huan
;
Zhu, Ya
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2021/11/04
SARS-CoV-2
natural products
virtual screening
spike protein
protein-protein interaction modulators
Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 417, 页码: 11
作者:
Geng, Huan
;
Zhou, Mengxue
;
Li, Bin
;
Liu, Liang
;
Yang, Xu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/08/17
Metal-drug nanoparticles
Orthotopic osteosarcoma
Osteolytic microenvironment
Zoledronate
Radiotherapy
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Ren, Peng-xuan
;
Shang, Wei-juan
;
Yin, Wan-chao
;
Ge, Huan
;
Wang, Lin
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/06/11
SARS-CoV-2 inhibitors
RdRp
host ribosome
Virus RNA