中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
广州生物医药与健康... [10]
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期刊论文 [37]
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2025 [3]
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Biochemis... [11]
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Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 22
作者:
Bai, Wenjing
;
Xu, Jinxin
;
Gu, Wenbin
;
Wang, Danyang
;
Cui, Ying
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:
Chen, Jiexuan
;
Wu, Mingfei
;
Mo, Jun
;
Hong, Ju
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10
作者:
Yu, Qian
;
Gao, Lixin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/12/11
Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 28
作者:
Duan, Haiting
;
Zhang, Jingyu
;
Gui, Renzhao
;
Lu, Yang
;
Pang, Ao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/20
A review of polybrominated diphenyl ethers and novel brominated flame retardants in Chinese aquatic environment: Source, occurrence, distribution, and ecological risk assessment
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 904, 页码: 14
作者:
Wang, Neng
;
Lai, Cui
;
Xu, Fuhang
;
Huang, Danlian
;
Zhang, Mingming
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/08/23
Novel brominated flame retardant
Polybrominated diphenyl ethers
Distribution
Risk assessment
Aquatic environment
Copper modified cobalt-chromium particles for attenuating wear particle induced-inflammation and osteoclastogenesis
期刊论文
OAI收割
BIOMATERIALS ADVANCES, 2023, 卷号: 147, 页码: 11
作者:
Lu, Yanjin
;
Xu, Xiongcheng
;
Yang, Chunguang
;
Hosseinkhani, Saman
;
Zhang, Chenke
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/07
Inflammation
Osteoclastogenesis
Osteoclast
Cu ion
Spatial and Temporal Patterns of Carbon and Water Use Efficiency on the Loess Plateau and Their Influencing Factors
期刊论文
OAI收割
LAND, 2023, 卷号: 12, 期号: 1, 页码: 16
作者:
Zhang, Qi
;
Lu, Jinxin
;
Xu, Xuexuan
;
Ren, Xiuzi
;
Wang, Junfeng
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/03/03
Loess Plateau
carbon and water use efficiency
climate change
human activities
Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15
作者:
Zhu, Cheng-Liang
;
Luo, Xiaomin
;
Tian, Tian
;
Rao, Zijian
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/16
AKT
Protein kinase B
PROTAC
Chemical degrader
Rational design
Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton's Tyrosine Kinase for the Treatment of Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9096–9125
作者:
Zhang, Jingyu
;
Che, Jinxin
;
Luo, Xiaomin
;
Wu, Mingfei
;
Kan, Weijuan
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2024/03/21