中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [45]
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期刊论文 [355]
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The synthesis and antileukemic activity of 5-substituted thiazolyl urea derivatives
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 115, 页码: 6
作者:
Peng, Cheng
;
Sheng, Li
;
Xu, Gao-Ya
;
Qi, Xiao-Lei
;
Zhou, Yu-Bo
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/12/25
Antileukemic
Thiazolyl
Urea
Synthesis
SAR
Development of ketalized unsaturated saccharides as multifunctional cysteine-targeting covalent warheads
期刊论文
OAI收割
COMMUNICATIONS CHEMISTRY, 2024, 卷号: 7, 期号: 1, 页码: 10
作者:
Dong, Sanfeng
;
Huang, Hui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/10/21
Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16
作者:
Li, Xiaomei
;
Zhang, Hui
;
Dong, Sanfeng
;
Gao, Xuejie
;
Sun, Haiguo
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/09/26
Multiple myeloma
1-amido-2-one-4-thio-deoxypyranose
TRIP13 inhibitor
In vivo activity
Design, synthesis and structure-activity relationship of 1,8-naphthalimide derivatives as highly potent hCYP1B1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 8
作者:
Wei, Yueyue
;
Xiong, Yuan
;
Liao, Qingyi
;
Yang, Ya
;
Tian, Tian
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/07/12
8-naphthalimide
Structure -activity relationships (SAR)
Paclitaxel (PTX) resistance
Molecular docking
Scintillation Arc from FRB 20220912A
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2024, 卷号: 67, 期号: 1
作者:
Wu, Zi-Wei
;
Main, Robert A.
;
Zhu, Wei-Wei
;
Zhang, Bing
;
Jiang, Peng
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/29
fast radio burst
scintillation
FRB 20220912A
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11
作者:
Zhao, Yitian
;
Zhang, Min
;
Hou, Xudong
;
Han, Jiaxin
;
Qin, Xiaoya
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/10/17
Salicylanilide
hPL inhibitor
Structure -activity relationship
Anti -obesity
A Spectral-timing Study of the Inner Flow Geometry in MAXI J1535-571 with Insight-HXMT and NICER
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2023, 卷号: 953, 期号: 2, 页码: 12
作者:
Yu, Wei
;
Bu, Qing-Cui
;
Liu, He-Xin
;
Huang, Yue
;
Zhang, Liang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/11/14
Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
;
Zhu, Guanghao
;
Sun, Mengru
;
Zou, Kun
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity