机构

• 上海药物研究所 [16]
• 大连化学物理研究所 [1]
• 深海科学与工程研究所 [1]

采集方式

• OAI收割 [18]

内容类型

• 期刊论文 [17]
• 会议论文 [1]

发表日期

• 2025 [2]
• 2024 [4]
• 2023 [3]
• 2022 [3]
• 2021 [3]
• 2019 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共18条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structural insights into the activation of TMEM175 by small molecule 期刊论文  OAI收割 NEURON, 2025, 卷号: 113, 期号: 21, 页码: 25 作者:  Zhu, Xuewu;  Ping, Meixuan;  Liu, Heng;  Yu, Ting;  Jiang, Zhongwen   |  收藏  |   Discovery of Novel RNA Demethylase FTO Inhibitors Featuring an Acylhydrazone Scaffold with Potent Antileukemia Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 22 作者:  Liang, Xuewu;  Huang, Yue;  Ren, Hairu;  Liu, Qi;  Chen, Liang   |  收藏  |   Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 17, 页码: 15220-15245 作者:  Saidahmatov, Abdusaid;  Li, Jianan;  Xu, Shihao;  Hu, Xiaobei;  Gao, Xiangqian   |  收藏  |   Discovery of Novel Pyrimidine-Based Derivatives as Nav1.2 Inhibitors with Efficacy in Mouse Models of Epilepsy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12912-12931 作者:  He, Guoxue;  Zheng, Yueming;  Chang, Shunzhen;  Wang, Long;  Yang, Xiaohao   |  收藏  |   Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661 作者:  Li, Yuan;  Xu, Tingting;  Zhao, Yue;  Zhang, Hui;  Liu, Zesheng   |  收藏  |   Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906 作者:  Liang, Xuewu;  Yu, Haolan;  Liang, Renwen;  Feng, Zhuanghui;  Saidahmatov, Abdusaid   |  收藏  |   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |   The new direction of drug development: Degradation of undruggable targets through targeting chimera technology 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54 作者:  Liang, Xuewu;  Ren, Hairu;  Han, Fengyang;  Liang, Renwen;  Zhao, Jiayan   |  收藏  |   Construction of Diversified Penta-Spiro-Heterocyclic and Fused-Heterocyclic Frameworks with Potent Antitumor Activity 期刊论文  OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2023, 页码: 7 作者:  Liu, Qi;  Liu, Xuyi;  Li, Yazhou;  Zhou, Yu;  Zhao, Linxiang   |  收藏  |   Discovery of Novel Imidazo[4,5-c]quinoline Derivatives to Treat Inflammatory Bowel Disease (IBD) by Inhibiting Multiple Proinflammatory Signaling Pathways and Restoring Intestinal Homeostasis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21 作者:  Liang, Xuewu;  Xie, Yongle;  Liu, Xuyi;  Xu, Hui;  Ren, Hairu   |  收藏  |