中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
西北高原生物研究所 [18]
天津工业生物技术研... [12]
上海药物研究所 [8]
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化学研究所 [2]
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期刊论文 [58]
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2024 [1]
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2021 [4]
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2017 [9]
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Isotopic insights and integrated analysis for heavy metal levels, ecological risks, and source apportionment in river sediments of the Qinghai-Tibet Plateau
期刊论文
OAI收割
ENVIRONMENTAL RESEARCH, 2024, 卷号: 251, 页码: 118626
作者:
Cai, Na
;
Wang, Xueping
;
Zhu, Haixia
;
Hu, Yan
;
Zhang, Xiying
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/06/17
Heavy metals
Sediment
Qinghai -Tibet plateau (QTP)
Potential ecological risk
Sources
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Jiang, Xiangrui
;
Su, Haixia
;
Shang, Weijuan
;
Zhou, Feng
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2024/03/25
Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13
作者:
Yang, Hanxi
;
You, Mengyuan
;
Shu, Xiaoyang
;
Zhen, Jingyao
;
Zhu, Mengwei
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/10/17
Peptidomimetics
Benzothiazolyl ketone
3CLpro inhibitor
Pharmacokinetic properties
SARS-CoV-2
Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12
作者:
Zhu, Mengwei
;
Fu, Tiantian
;
You, Mengyuan
;
Cao, Junyuan
;
Yang, Hanxi
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
COVID-19
SARS-CoV-2
3CL protease
Nirmatrelvir
Peptidomimetic inhibitors
Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors
期刊论文
OAI收割
NATURE CHEMISTRY, 2023, 页码: 18
作者:
Guo, An-Di
;
Yan, Ke-Nian
;
Hu, Hao
;
Zhai, Linhui
;
Hu, Teng-Fei
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/10/17
Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 207, 页码: 16
作者:
Gao, Jing
;
Zhou, Chen
;
Zhong, Yan
;
Shi, Li
;
Luo, Xuanyang
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2023/04/10
HSP90
ATP competitive inhibitors
Tip-based affinity selection-mass spectrometry
Dipyridamole
Cell cycle regulators
Treatment of fishery wastewater by co-culture of Thalassiosira pseudonana with Isochrysis galbana and evaluation of their active components
期刊论文
OAI收割
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2021, 卷号: 60, 页码: 8
作者:
Wang, Haixia
;
Qi, Mei
;
Bo, Yahui
;
Zhou, Chengxu
;
Yan, Xiaojun
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/12/02
Fishery wastewater
Thalassiosira pseudonana
Isochrysis galbana
Co-culture
Active components
Quantification of temperature and precipitation changes in northern China during the "5000-year" Chinese History
期刊论文
OAI收割
QUATERNARY SCIENCE REVIEWS, 2021, 卷号: 255, 页码: 11
作者:
Zhang, Can
;
Zhao, Cheng
;
Zhou, Aifeng
;
Zhang, Haixia
;
Liu, Weiguo
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/05/21
Quantitative temperature
Quantitative precipitation
brGDGTs
Cultural changes
Chinese loess plateau
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
期刊论文
OAI收割
AUTOPHAGY, 2021, 卷号: 17
作者:
Klionsky, Daniel J.
;
Abdel-Aziz, Amal Kamal
;
Abdelfatah, Sara
;
Abdellatif, Mahmoud
;
Abdoli, Asghar
  |  
收藏
  |  
浏览/下载:327/0
  |  
提交时间:2021/05/31
Autophagosome
cancer
flux
LC3
lysosome
macroautophagy
neurodegeneration
phagophore
stress
vacuole
Quantification of temperature and precipitation changes in northern China during the 5000-year Chinese History
期刊论文
OAI收割
QUATERNARY SCIENCE REVIEWS, 2021, 卷号: 255
作者:
Zhang, Can
;
Zhao, Cheng
;
Zhou, Aifeng
;
Zhang, Haixia
;
Liu, Weiguo
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/03/10