中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Structural and configurational optimization of spacecrafts in Very Low Earth Orbit using Atmosphere-Breathing Electric Propulsion
期刊论文
OAI收割
ACTA ASTRONAUTICA, 2025, 卷号: 233, 页码: 82-98
作者:
Li XQ(李晓琪)
;
Geng JY(耿金越)
;
Yue YX(岳宇贤)
;
Han, Ning
;
Sun WJ(孙文进)
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2025/06/23
Very Low Earth Orbit (VLEO)
Atmosphere-Breathing Electric Propulsion (ABEP)
Structural and configurational optimization
Propellant balance
Power balance
Higher strength of double-double over traditional quad laminates in equal-stiffness design of single lap joint
期刊论文
OAI收割
THIN-WALLED STRUCTURES, 2025, 卷号: 213, 页码: 16
作者:
Huang, Yizhou
;
Qiu C(邱诚)
;
He, Zongkai
;
Hu, Yile
;
Sun, Guangyong
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/05/19
Double-double laminate
Single-lap joint
DIC testing
FEM analysis
Exploration of thermo-fluid-heat transfer evolution in salt cavern compressed air energy storage system under high-frequency injection and production conditions
期刊论文
OAI收割
TUNNELLING AND UNDERGROUND SPACE TECHNOLOGY, 2025, 卷号: 162, 页码: 10
作者:
Huang, Jun
;
Ge, Xinbo
;
Ma, Hongling
;
Shi, Xilin
;
Li, Yinping
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2025/06/27
Salt cavern
Compressed air energy storage
High-frequency injection and production
Thermo-fluid-heat transfer
Dynamic evolution
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
Effect of microalloying with La and Nd on adiabatic shear behavior in ultra-coarse grained Cu alloy under quasistatic tensile loading
期刊论文
OAI收割
MATERIALS CHARACTERIZATION, 2025, 卷号: 225, 页码: 13
作者:
Zhang, Mingyi
;
Chen, Kunyu
;
Li, Yang
;
Wang, Wei
;
Zhang, Lehui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/07/22
Adiabatic shear bands
Cu alloy
Deformation mechanism
Multi-scale
Rare earth
Development of Orally Bioavailable FTO Inhibitors with Potent Antileukemia Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 13, 页码: 13714-13727
作者:
Yang, Teng
;
Dong, Ze
;
Du, Rong
;
Wang, Yiqing
;
Liu, Lu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Bacterial Membrane Vesicles as Heteroantigen Reservoirs for Potentiated Colorectal Cancer Immunotherapy
期刊论文
OAI收割
ACS NANO, 2025, 卷号: 19, 期号: 26, 页码: 23760-23777
作者:
Liu, Chang
;
Yang, Canyu
;
Jiang, Xiuxian
;
Lu, Xiang
;
Huang, Xiaoyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
immunotherapy
bacterial membrane vesicle
heteroantigen reservoir
PD-L1 siRNA
immune checkpointblockade
Nanohydroxyapatite-Stabilized Pickering-Emulsion-Incorporated Hydrogel Prevents Postoperative Osteosarcoma Recurrence and Promotes Bone Repair
期刊论文
OAI收割
NANO LETTERS, 2025, 卷号: 25, 期号: 26, 页码: 10487-10496
作者:
Zhang, Yi
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
osteosarcoma
injectable hydrogel
nanohydroxyapatite
Pickering emulsion
RANKL inhibitor
bone regeneration
Ginsenoside (20)S-APPT induces ferroptosis in hepatocellular carcinoma and cholangiocarcinoma by targeting FSP1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 18
作者:
Liu, Fan-yu
;
Yang, Yuan-jie
;
Wang, Xue-long
;
Hong, Yan
;
Ou-Yang, Xiao-peng
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20