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浏览/检索结果: 共15782条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML) 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17 作者:  Mo, Jun;  Wang, Yuxian;  Pan, Youlu;  Xiao, Qitao;  Zhao, Jinyi   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/08/20 Menin  High binding affinity  Anti-proliferation activity  AML   Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24 作者:  Li, Na;  Wang, Linlin;  Hu, Xinyuan;  Xu, Haiyan   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/08/20 Voltage-gated sodium channel 1.8  Conformational restriction  Pharmacokinetic  Structure-activity relationship  Analgesic   Deciphering multi-media occurrence and anthropogenic drivers of potentially toxic elements in a rapidly urbanized estuary: A neural network-enhanced source apportionment 期刊论文  OAI收割 MARINE POLLUTION BULLETIN, 2025, 卷号: 218, 页码: 118178 作者:  Wang, Weili;  Lin, Yuhong;  Pan, Zhong;  Liu, Yang;  Wang, Lingqing   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/07/18 Bioaccumulation  Pollution characteristics  Multimedia  Ecological risk  Source   Polycomponent metal-organic frameworks of substituent polydispersion hydroxypropyl-β-cyclodextrin as inhalable drug carrier 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2025, 卷号: 362, 页码: 12 作者:  He, Xiaojian;  Xu, Huipeng;  Zhao, Xiangyu   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/07/25 Metal-organic frameworks  Polycomponent  Hydroxypropyl-beta-cyclodextrin  Polydispersion  Inhalation delivery   Electrokinetic transport mechanisms of rare earth elements in ion-adsorption deposits: An integrated model approach 期刊论文  OAI收割 ENVIRONMENTAL TECHNOLOGY & INNOVATION, 2025, 卷号: 39, 页码: 15 作者:  Xu, Jie;  Wang, Gaofeng;  Ling BW(凌博闻);  Kang SZ(康石长);  Yang, Yongqiang   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/08/18 Rare earth elements  Ion-adsorption rare earth deposits  Electrokinetic mining  Electrokinetic transport mechanism  Numerical simulation   Immunosuppressive nitrogen-containing triterpenoid saponins from Mussaenda erosa and the therapeutic efficacy of heinsiagenin A in a murine lupus erythematosus model 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 11 作者:  Xu, Yidan;  Xiang, Mai;  Chang, Yuan;  Chen, Zhenhua;  Zhang, Rujun   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/08/20 Mussaenda erosa  Nitrogen-containing triterpenoid saponins  Immunosuppressive activity  Autoimmune diseases  Heinsiagenin A   EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow 期刊论文  OAI收割 ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1 作者:  Jiang, Shuai-Qing;  Xu, Dong;  Hoof, Agnes P. C. van;  Lei, Wei-Hua;  Liu, Yuan   |  收藏  |  浏览/下载：20/0  |  提交时间：2025/07/28 Advances in Sampling and Analytical Techniques for Single-Cell Metabolomics: Exploring Cellular Heterogeneity 期刊论文  OAI收割 RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2025, 卷号: 39, 期号: 13, 页码: 14 作者:  Shen, Xinxin;  Zhang, Fangyuan;  Tang, Chunping;  Sokovic, Marina;  Misic, Danijela   |  收藏  |  浏览/下载：17/0  |  提交时间：2025/06/23 cell isolation  mass spectrometry imaging  metabolite detection  sampling techniques  single-cell metabolomics   Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20 作者:  Zheng, Fuqiang;  Hu, Zhengtao   |  收藏  |  浏览/下载：23/0  |  提交时间：2025/06/23 Heterocycle-fused phenylcyclohexylamines  Multi-target antagonists  NMDAR  Monoamine transporter  Antidepressants   Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins 期刊论文  OAI收割 SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7 作者:  Cao, Zhen;  Aharonian, F.;  Axikegu;  Bai, Y. X.;  Bao, Y. W.   |  收藏  |  浏览/下载：33/0  |  提交时间：2025/06/10 gamma rays  cosmic rays  supernova remnant  young massive cluster  pulsar