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Chinese Academy of Sciences Institutional Repositories Grid
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Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4739-4756
作者:
Zhong, Ye
;
Xu, Jing
;
Zhou, Ruochen
;
Tang, Li
;
Ding, Shaoyue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/05/07
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Addition of a-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 16
作者:
Yang, Ze-xian
;
Zhang, Yu
;
Wang, Qing
;
Zhang, Lei
;
Liu, Yi-fei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Parkinson's disease
gut-brain axis
a-Synuclein
inflammation
microbiota
intestinal mouse coloclysis model
Development of a multiple convolutional neural network-facilitated diagnostic screening program for immunofluorescence images of IgA nephropathy and idiopathic membranous nephropathy
期刊论文
OAI收割
CLINICAL KIDNEY JOURNAL, 2023, 页码: 11
作者:
Xia, Peng
;
Lv, Zhilong
;
Wen, Yubing
;
Zhang, Baichuan
;
Zhao, Xuesong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/04
convolutional neural network
idiopathic membranous nephropathy
IgA nephropathy
immunofluorescence
Histopathological bladder cancer gene mutation prediction with hierarchical deep multiple-instance learning
期刊论文
OAI收割
MEDICAL IMAGE ANALYSIS, 2023, 卷号: 87, 页码: 13
作者:
Yan, Rui
;
Shen, Yijun
;
Zhang, Xueyuan
;
Xu, Peihang
;
Wang, Jun
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/04
Bladder cancer
Contrastive learning
Gene mutation prediction
Histopathological image analysis
Multiple instance learning
Bisphenol A (BPA) Directly Activates the G Protein-Coupled Estrogen Receptor 1 and Triggers the Metabolic Disruption in the Gonadal Tissue of Apostichopus japonicus
期刊论文
OAI收割
BIOLOGY-BASEL, 2023, 卷号: 12, 期号: 6, 页码: 19
作者:
Yuan, Jieyi
;
Yang, Jingwen
;
Xu, Xiuwen
;
Wang, Zexianghua
;
Jiang, Zhijing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
Apostichopus japonicus
reproduction
estradiol receptor
Bisphenol A (BPA)
metabolic disruption
Scalable and Conflict-Free NTT Hardware Accelerator Design: Methodology, Proof, and Implementation
期刊论文
OAI收割
IEEE TRANSACTIONS ON COMPUTER-AIDED DESIGN OF INTEGRATED CIRCUITS AND SYSTEMS, 2023, 卷号: 42, 期号: 5, 页码: 1504-1517
作者:
Mu, Jianan
;
Ren, Yi
;
Wang, Wen
;
Hu, Yizhong
;
Chen, Shuai
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/04
Memory access pattern
number theoretic transform (NTT)
post-quantum cryptography (PQC)
scalable hardware design
Satellite Remote Sensing of Global Land Surface Temperature: Definition, Methods, Products, and Applications
期刊论文
OAI收割
REVIEWS OF GEOPHYSICS, 2023, 卷号: 61, 期号: 1, 页码: 77
作者:
Li, Zhao-Liang
;
Wu, Hua
;
Duan, Si-Bo
;
Zhao, Wei
;
Ren, Huazhong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/09
Atlas of dynamic spectra of fast radio burst FRB 20201124A
期刊论文
OAI收割
CHINESE PHYSICS B, 2023, 卷号: 32, 期号: 2
作者:
Wang, Bo-Jun
;
Xu, Heng
;
Jiang, Jin-Chen
;
Xu, Jiang-Wei
;
Niu, Jia-Rui
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/03/20
fast radio burst
FAST
Rapid identification of fish species by laser-induced breakdown spectroscopy and Raman spectroscopy coupled with machine learning methods
期刊论文
OAI收割
FOOD CHEMISTRY, 2023, 卷号: 400, 页码: 9
作者:
Ren, Lihui
;
Tian, Ye
;
Yang, Xiaoying
;
Wang, Qi
;
Wang, Leshan
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/01/12
Fish species identification
laser -induced breakdown spectroscopy (LIBS)
Raman spectroscopy
Machine learning
convolutional neural network (CNN)
Data fusion