中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [186]
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Guiding precision medicine strategy for intravenous ginsenosides via pharmacokinetic-informed bioinformatic approaches: a study on XueShuanTong
期刊论文
OAI收割
PHYTOMEDICINE, 2025, 卷号: 143, 页码: 18
作者:
Jia, Wei-Wei
;
Tian, Nan-Nan
;
Song, Zi-Jing
;
Lan, Xiao-Fang
;
Yang, Xi-He
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Precision medicine
Physiologically based pharmacokinetic model
Ginsenoside
Albumin-facilitated dissociation
Drug interaction
Drug transporter
Hepatic impairment
Phytochemical and biological studies on rare and endangered plants endemic to China. Part XLIV. Integrated NMR/EI-MS/LC-PDA-ESIMS approach for dereplication and targeted isolation of fortunefuroic acids from
Keteleeria
fortunei
across diverse geographical origins
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 235, 页码: 13
作者:
Zhao, Ze-Yu
;
Jiang, Zhe-Lu
;
Tong, Ying-Peng
;
Chi, Chun-Jing
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/04/24
Keteleeria fortunei
Pinaceae
Geographical origins
Integrated NMR/EI-MS/LC-PDA-ESIMS
methods
Fortunefuroic acids
ATP-Citrate lyase
Native Ligand-Inspired peptides for c-MET targeted PET probes development
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2025, 页码: 18
作者:
Luo, Renli
;
Tan, Boyu
;
Zhang, Ying
;
Hu, Jing
;
Lin, Jia
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
C-MET
Native ligand
HGF
PET/CT imaging
Radiopharmaceuticals
Peptide probes
Triconnarins A-D: Four Secophragmalin-Type Limonoids from the Twigs and Leaves of
Trichilia connaroides
期刊论文
OAI收割
ORGANIC LETTERS, 2025, 卷号: 27, 期号: 25, 页码: 6772-6776
作者:
Xu, Jia-Xin
;
Zhao, Hai-Yang
;
Li, Xiao-Zhou
;
Li, Zhi-Ying
;
Shen, Tao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Radiative forcing reduced by early twenty-first century increase in land albedo
期刊论文
OAI收割
NATURE, 2025, 卷号: 641, 期号: 8065
作者:
Hou, Zhengyang
;
Zhang, Liqiang
;
Peng, Jingjing
;
Forzieri, Giovanni
;
Jia, Aolin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/07/18
PRL-3: unveiling a new horizon in cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 11
作者:
Cao, Zi-tong
;
Mao, Jia-luo
;
Huang, Chang-ying
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/06/23
Phosphatase of Regenerating Liver-3 (PRL3)
tumor metastasis
targeted therapies
PRL-3-zumab
A Phase I Study to Evaluate the Pharmacokinetics and Safety of TPN171 (a PDE5 Inhibitor) in Adults with Renal Impairment
期刊论文
OAI收割
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2025, 页码: 8
作者:
Fu, Ping
;
Song, Yi
;
Hu, Chao
;
Yong, Xiaolan
;
Yu, Yang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/06/23
pharmacokinetics
phosphodiesterase 5 inhibitor
renal impairment
safety
TPN171
Glabridin as a selective Kv2.1 inhibitor ameliorates DPN pathology by disrupting the Aβ/Kv2.1/JNK/NF-κB/NLRP3/p-Tau pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 17
作者:
Xu, Jia-wen
;
Ma, Lin
;
Xiang, Yu
;
Dai, Meng-qing
;
Li, Qiu-hui
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/05/27
diabetic peripheral neuropathy
glabridin
Kv2.1
dorsal root ganglia
Schwann cells
A beta/Kv2.1/NLRP3/p-Tau axis
REG3A secreted by peritumoral acinar cells enhances pancreatic ductal adenocarcinoma progression via activation of EGFR signaling
期刊论文
OAI收割
CELL COMMUNICATION AND SIGNALING, 2025, 卷号: 23, 期号: 1, 页码: 19
作者:
Ren, Xiaojing
;
Teng, Yunfei
;
Xie, Kunxin
;
He, Xiao
;
Chen, Gang
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/04/01
REG3A
Pancreatic ductal adenocarcinoma
Peritumoral acinar cell
Epidermal growth factor receptor (EGFR)
Paracrine
Identification of oligosaccharide isomers using electrostatically asymmetric nanopore
期刊论文
OAI收割
BIOPHYSICAL JOURNAL, 2025, 卷号: 124, 期号: 3, 页码: 393A-393A
作者:
Li, Yaxue
;
Gao, Fan
;
Wang, Jia-Hong
;
Wen, Liuqing
;
Long, Yi-Tao
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/08/20