中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [106]
近代物理研究所 [27]
合肥物质科学研究院 [12]
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期刊论文 [323]
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From Hit to Lead: Discovery of Novel Selective RIPK1 Inhibitor with Pyridoimidazole Scaffold for the Treatment of Autoimmune Diseases through Phenotypic Screening and Structural Optimization
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 69, 期号: 3, 页码: 3252-3288
作者:
Wan, Jihong
;
Xiong, Xiao-Yu
;
Geng, Zixiang
;
Yuan, Benjun
;
Ma, Youzhen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2026/04/01
Targeting intrinsic and CAF-mediated signaling by PI3Kα inhibitor CYH33 attenuated metastasis in lung squamous cell carcinoma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2026, 页码: 14
作者:
Ma, Xiao-yu
;
Deng, Jie-ting
;
Cao, Zhe-rui
;
Xu, Lan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2026/04/01
LUSC
CYH33
PI3K alpha
CAF
metastasis
Characteristics and controlling factors of stable isotopes in precipitation based on 9-year monitoring data in the monsoon transition zone of the Tibetan Plateau
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2026, 卷号: 376, 页码: 15
作者:
Shao-yong, Wang
;
Qiao-li, Wang
;
Shi-chang, Kang
;
Yong-jian, Ding
;
Yu-ang, Xue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/12/22
Tibetan plateau
Precipitation
Stable isotope
Controlling factor
Moisture source
BMAL1/PGC1a4-FNDC5/irisin axis impacts distinct outcomes of time-of-day resistance exercise
期刊论文
OAI收割
JOURNAL OF SPORT AND HEALTH SCIENCE, 2025, 卷号: 14, 页码: 23
作者:
Guo, Mingwei
;
Shen, Fei
;
Guo, Xiaozhen
;
Zhang, Jun
;
Ma, Ying
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收藏
  |  
浏览/下载:216/0
  |  
提交时间:2025/04/01
Daily variance
Circadian
Muscle strength
Metabolic benefits
Resistance exercise
The interplay between tissue-resident microbiome and host proteins by integrated multi-omics during progression of colorectal adenoma to carcinoma
期刊论文
OAI收割
IMETA, 2025, 页码: 37
作者:
Wu, Di
;
Wang, An-Jun
;
Bu, De-Chao
;
Sun, Yan-Yan
;
Li, Chen-Hao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/12/03
colorectal cancer
metagenomics
microbiota-host interaction
proteomics
tissue-resident microbiome
Substantial reductions in black carbon from both fossil fuels and biomass burning during China's Clean Air Action
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2025, 卷号: 122, 期号: 35, 页码: 7
作者:
Liu, Junwen
;
Jiang, Fan
;
Wang, Qiongqiong
;
Zhang, Gan
;
Li, Jun
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/10/13
black carbon
isotope evidence
emission inventory
Clean Air Action
Spectral Hardening Reveals Afterglow Emergence in Long-duration Fast X-Ray Transients: A Case Study of GRB 250404A/EP250404a
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 989, 期号: 2, 页码: L39
作者:
Yin, Yi-Han Iris
;
Fang, Yuan
;
Zhang, Bin-Bin
;
Deng, Chen
;
Yang, Jun
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收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/10/09
Dual targeting of VEGFR2 and CSF1R with SYHA1813 confers novel strategy for treating both BRAF wild-type and mutant melanoma
期刊论文
OAI收割
CANCER CELL INTERNATIONAL, 2025, 卷号: 25, 期号: 1, 页码: 12
作者:
Shi, Wenhao
;
Tang, Haotian
;
Tong, Linjiang
;
Song, Peiran
;
Huang, Yuqing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/12/04
SYHA1813
Melanoma
VEGFR2
CSF1R
Metastasis
Vemurafenib
Resolving the Snowball Earth conundrum: the role of marine dissolved organic carbon pool
期刊论文
OAI收割
SCIENCE BULLETIN, 2025, 卷号: 70, 期号: 13, 页码: 2173-2189
作者:
Shen, Bing
;
Lang, Xianguo
;
Wang, Ruimin
;
Liu, Yonggang
;
Zhang, Shihong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/09/23
Snowball Earth
Waterbelt
Carbon cycle
Dissolved Organic Carbon (DOC)
USP7 V517F mutation as a mechanism of inhibitor resistance
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 14
作者:
Miao, Yu-Ling
;
Fan, Fengying
;
Cheng, Yong-Jun
;
Jia, Li
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2025/05/27