中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [48]
昆明植物研究所 [18]
近代物理研究所 [18]
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合肥物质科学研究院 [12]
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期刊论文 [270]
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浏览/检索结果:
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Mass balance, metabolism, and pharmacokinetics of [
14
C]amdizalisib, a clinical-stage novel oral selective PI3Kδ inhibitor for the treatment of non-hodgkin's lymphoma, in healthy Chinese volunteers
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Zhao, Chun-Yang
;
Zhang, Li-Jun
;
Sun, Chan
;
Yu, Cheng-Yin
;
Wang, Jian
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/01/06
amdizalisib
PI3K delta kinase
metabolism
mass balance
metabolite identification
pharmacokinetics
safety
Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 277, 页码: 17
作者:
Zhuang, Zhen
;
Miao, Yu-Ling
;
Song, Shan-Shan
;
Leng, Guang-Tong
;
Zhang, Xiao-Fei
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/09/26
USP7 inhibitor
Structure-activity relationships
Anti-cancer
pyrrolo[2,3-d]pyrimidin-4-one
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/09/10
Lower Devonian conodonts from the Xainza area, central Tibet and the Lower Devonian stage boundaries in China
期刊论文
OAI收割
PALAEOWORLD, 2024, 卷号: 33, 期号: 3, 页码: 584-597
作者:
Guo, Wen
;
Song, Jun -Jun
;
Lu, Jian-Feng
;
Huang, Jia-Yuan
;
Wang, Yu-Jue
  |  
收藏
  |  
浏览/下载:140/0
  |  
提交时间:2024/08/28
Abstract
Conodont
Biostratigraphy
Lower Devonian
Lhasa Block
Tibet
Pragian conodont zonal subdivision ( sulcatus
kindlei
pire
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
;
Ren, Chao
;
Li, Mu-zi
;
Liu, Yi-hui
;
Yao, Ren-qi
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
The nearest neutron star candidate in a binary revealed by optical time-domain surveys
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2023, 卷号: 66, 期号: 12
作者:
Zheng, Ling-Lin
;
Sun, Mouyuan
;
Gu, Wei-Min
;
Yi, Tuan
;
Zhang, Zhi-Xiang
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2024/03/29
neutron stars
binary stars
stellar evolution
Modeling of breaching parameters for debris flow dams
期刊论文
OAI收割
JOURNAL OF MOUNTAIN SCIENCE, 2023, 卷号: 20, 期号: 10, 页码: 2835-2851
作者:
Ruan, He-chun
;
Chen, Hua-yong
;
Chen, Xiao-qing
;
Zhao, Wan-yu
;
Chen, Jian-gang
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2024/03/14
Debris flow dams
Overtopping failure
Breaching parameters
Peak discharge
Flume experiment
Variability of Magnetic Hot Stars from the TESS Observations
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2023, 卷号: 955, 期号: 2, 页码: 123
作者:
Shen, Dong-Xiang
;
Li, Gang
;
Abdusamatjan, Iskandar
;
Fu, Jian-Ning
;
Zhu, Chun-Hua
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/10
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Wu, Chun-mei
;
Mao, Jia-wen
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/10/17
dry eye disease
DZ2002
corneal angiogenesis
immunomodulatory function
NF-kappa B
ophthalmic therapy
Crude oil cracking in deep reservoirs: A review of the controlling factors and estimation methods
期刊论文
OAI收割
PETROLEUM SCIENCE, 2023, 卷号: 20, 期号: 4, 页码: 1978-1997
作者:
Qi, Yu
;
Cai, Chun-Fang
;
Sun, Peng
;
Wang, Dao-Wei
;
Zhu, Hong-Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/12/29
Oil cracking
Deep reservoir
Controlling factor
Gas to oil ratio
Diamondoid