中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共31条,第1-10条 帮助

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Rational engineering of degradation tail-driven CELMoD-antibody conjugates for precision malignancy therapy 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 12, 页码: 6510-6528
作者:  
Guo, Yu;  Song, Yi;  Wang, Hanlin;  Lu, Yang;  Zhang, Jingyu
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Modular PROTAC/IMiD Bifunctional Molecule Design for the Degradation of Synergistic Targets in the Treatment of Lymphoma 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 20, 页码: 21249-21281
作者:  
Jin, Yuheng;  Liao, Xueyan;  Zhang, Jingyu;  Duan, Haiting;  Xu, Ran
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Discovery of a Selective and Potent BCL6 PROTAC with Efficacious Antiproliferative Activity for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 19, 页码: 20180-20206
作者:  
Yu, Xiaoli;  Liao, Xueyan;  Zhang, Jingyu;  Wang, Hanlin;  Li, Xian
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Proteogenomic characterization of non-functional clinically relevant subgroups 期刊论文  OAI收割
CANCER CELL, 2025, 卷号: 43, 期号: 4, 页码: 36
作者:  
Ji, Shunrong;  Cao, Lihua;  Gao, Jing;  Du, Yang;  Ye, Zeng
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Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:  
Zeng, Gongruixue;  Xu, Gaoya;  Gao, Lixin;  Zheng, Xiaoli;  Chi, Xinglong
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Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679
作者:  
Jin, Yuheng;  Qi, Xuxin;  Yu, Xiaoli;  Cheng, Xirui;  Chen, Boya
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Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:  
Chen, Jiexuan;  Wu, Mingfei;  Mo, Jun
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Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10
作者:  
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Single-cell sequencing reveals the heterogeneity of pancreatic neuroendocrine tumors under genomic instability and histological grading 期刊论文  OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 9, 页码: 18
作者:  
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Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 28
作者:  
Duan, Haiting;  Zhang, Jingyu;  Gui, Renzhao
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