中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
ABHD6 drives endocytosis of AMPA receptors to regulate synaptic plasticity and learning flexibility
期刊论文
OAI收割
PROGRESS IN NEUROBIOLOGY, 2024, 卷号: 233, 页码: 17
作者:
Wei, Mengping
;
Yang, Lei
;
Su, Feng
;
Liu, Ying
;
Zhao, Xinyi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/25
AMPA receptors
ABHD6
Endocytosis
Synaptic plasticity
Learning flexibility
Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16
作者:
Han, Fanghui
;
Zhao, Tingting
;
Zhang, Yanglong
;
Yun, Ying
;
Xu, Yuanyuan
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/02/19
SSTR5 antagonist
Gallbladder emptying
Cholesterol gallstones
RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2024, 卷号: 43, 期号: 1, 页码: 15
作者:
Lin, Ying
;
Wu, Yun
;
Zhang, Qiangzu
;
Tu, Xunwei
;
Chen, Sufang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/20
Non-small cell lung cancer
Brain metastasis
RPTOR
SPHK2
S1P
Association between gaming disorder and regional homogeneity in highly involved male adult gamers: A pilot resting-state fMRI study
期刊论文
OAI收割
BRAIN AND BEHAVIOR, 2023, 页码: 12
作者:
Jiang, Wen-tao
;
Liu, Xia
;
Xu, Zi-yun
;
Zhou, Zhi-feng
;
Tie, Chang-jun
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/20
depression
gaming disorder
highly involved gamers
hippocampus
impulsivity
regional homogeneity
Original Research Response to programmed cell death protein 1 antibody in patients with Epstein-Barr virus-associated intrahepatic cholangiocarcinoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF CANCER, 2023, 卷号: 194, 页码: 9
作者:
He, Wen-Zhuo
;
Huang, Yu-Hua
;
Hu, Wan-Ming
;
Wang, Fang
;
Xu, Yu-Xia
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/12/11
Epstein-Barr virus
Intrahepatic cholangiocarcinoma
Programmed cell death protein 1
Immunotherapy
Aberrant degree centrality profiles during rumination in major depressive disorder
期刊论文
OAI收割
HUMAN BRAIN MAPPING, 2023, 页码: 13
作者:
Jia, Feng-Nan
;
Chen, Xiao
;
Du, Xiang-Dong
;
Tang, Zhen
;
Ma, Xiao-Yun
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/11/12
degree centrality
dorsal attention network
executive function
fMRI
major depressive disorder
rumination
Astaxanthin protected against the adverse effects induced by diesel exhaust particulate matter via improving membrane stability and anti-oxidative property (vol 456, 131684, 2023)
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2023, 卷号: 459
作者:
Wang, Tong
;
Liu, Ying
;
Zhou, Yemian
;
Liu, Qiao
;
Zhang, Qixing
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/10
Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23
作者:
Chen, Lili
;
Yun, Ying
;
Guo, Shimeng
;
Wang, Xiaoyan
;
Xiong, Muya
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Emergent failure transition of pearlitic steel at extremely high strain rates
期刊论文
OAI收割
COMPUTATIONAL MATERIALS SCIENCE, 2023, 卷号: 219, 页码: 13
作者:
Liang, Lun-Wei
;
Dai, Shi-Cheng
;
Chen, Yan
;
Wang, Hai-Ying
;
Wang, Yun-Jiang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/03/20
Pearlitic steels
Fracture
Crack
Dislocation nucleation
Molecular dynamics