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浏览/检索结果: 共209条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13 作者:  Tang, Mingze;  Zhou, Xuan;  Shen, Qianqian;  Fang, Chen;  Peng, Xia   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/08/22 Receptor -interacting protein kinase 1  Histone deacetylases  Inhibitor  Molecular dynamics (MD) simulation  ADMET analysis   Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 16 作者:  An, Yuxiang;  Peng, Xia;  Wang, Tianchen;  Liu, Kaiyuan;  Feng, Dazhi   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/12/25 inhibitor  pharmacokinetic study  pyridazin-4-one  receptor-interacting protein kinase 1  selectivity   How will climate change affect the sources of global irrigation water withdrawal? 期刊论文  OAI收割 SCIENCE BULLETIN, 2024, 卷号: 69, 期号: 21, 页码: 3361-3364 作者:  Ai, Zhipin;  Zhao, Xin;  Boulange, Julien;  Li, Fadong;  Mahmood, Rashid   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/12/20 Transcriptomic decoding of regional cortical vulnerability to major depressive disorder 期刊论文  OAI收割 COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12 作者:  Zhu, Jiajia;  Chen, Xiao;  Lu, Bin;  Li, Xue-Ying;  Wang, Zi-Han   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/09/10 Design, synthesis, and structure-activity relationship studies of 6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole derivatives as necroptosis inhibitors 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2024, 卷号: 15, 期号: 7, 页码: 2514-2526 作者:  Jin, Zechen;  Dai, Yang;  Ji, Yinchun;  Peng, Xia;  Duan, Wenhu   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/08/20 Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 21 作者:  Lan, Yaohan;  Ji, Yinchun;  Peng, Xia;  Duan, Wenhu;  Geng, Meiyu   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/08/22 autoimmune disease  necroptosis inhibitor  pharmacokinetic profile  receptor interacting protein kinase 1 (RIPK1)  structural optimization   Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：31/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183 作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/02/27 Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13 作者:  Zhou, Ji;  Zhang, Xu-Chao;  Xue, Shan;  Dai, Mengdi;  Wang, Yueliang   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/10/17