机构

• 上海药物研究所 [45]
• 化学研究所 [4]
• 西安光学精密机械研究... [4]
• 古脊椎动物与古人类研... [3]
• 力学研究所 [2]
• 大连化学物理研究所 [2]
• 更多

采集方式

• OAI收割 [65]

内容类型

• 期刊论文 [65]

发表日期

• 2026 [1]
• 2025 [6]
• 2024 [7]
• 2023 [3]
• 2022 [6]
• 2021 [5]
• 更多

学科主题

• Immunology [2]

筛选

浏览/检索结果: 共65条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Novel thieno[2,3-b]pyridine derivatives protect islet through DRAK2 kinase inhibition 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 301, 页码: 18 作者:  Lian, Kaiyue;  Li, Ruihan;  Lu, Yuting;  Song, Gaolei;  Zhang, Xinwen   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/12/04 DRAK2  Inhibitor  Thieno[2  b ]pyridine  Diabetes   The enedioic acid analog 326E alleviates metabolic dysfunction-associated steatohepatitis via dual targeting at ACLY and PPARα 期刊论文  OAI收割 CELL METABOLISM, 2025, 卷号: 37, 期号: 11, 页码: 2149-2166 作者:  Xie, Zhifu;  Cheng, Long;  Hu, Yue;  Song, Gaolei;  Wang, Fan   |  收藏  |  浏览/下载：1/0  |  提交时间：2026/01/28 Mechanism of hydroxamic acid group metabolism to carboxylic acid: Oxidation versus hydrolysis 期刊论文  OAI收割 DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 10, 页码: 11 作者:  Huang, Xiyue;  Zhou, Lei;  Chen, Huixian;  Sun, Xiaowei;  Cao, Mengyi   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/12/04 Hydroxamic acid group  Bisthianostat  HDAC inhibitor  Cytochrome P450 enzymes  Oxidative cleavage   Discovery of Novel Tridentate Alkenyl Diacid Derivatives as Potent ATP Citrate Lyase Inhibitors for the Treatment of Hepatocellular Carcinoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 15, 页码: 15598-15616 作者:  Yang, Yurou;  Zhai, Jimao;  Wang, Fan;  Song, Gaolei;  Xu, Honghong   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/09/09 Effects of cracked semi-infinite ice sheets on the wave excited motion of a body floating on water 期刊论文  OAI收割 OCEAN ENGINEERING, 2025, 卷号: 325, 页码: 18 作者:  Zhang, Mohan;  Xiao, Runshan;  Xue, Zhen;  Yu, Fajun   |  收藏  |  浏览/下载：50/0  |  提交时间：2025/04/07 Phosphatidylinositol 4,5-bisphosphate activation mechanism of human KCNQ5 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2025, 卷号: 122, 期号: 14, 页码: 11 作者:  Yang, Zhenni;  Zheng, Yueming;  Ma, Demin;  Wang, Long;  Zhang, Jiatong   |  收藏  |  浏览/下载：40/0  |  提交时间：2025/06/23 KCNQ  PIP2  ligand activation  structure  mechanism   A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects 期刊论文  OAI收割 DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 1783-1794 作者:  Liu, Yun;  Yu, Chengyin;  Zhang, Yifan;  Xie, Zhifu;  Wang, Yating   |  收藏  |  浏览/下载：28/0  |  提交时间：2025/04/24 safety  tolerability  pharmacokinetics  pharmacodynamics  BGT-002  novel ACLY inhibitor   Discovery of Alkyl Conjugated Diene Diacids as Novel ACLY Inhibitors 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 11, 页码: 3476-3489 作者:  Cheng, Tingting;  Song, Gaolei;  Cheng, Long;  Wang, Fan;  Sun, Xinyu   |  收藏  |  浏览/下载：62/0  |  提交时间：2025/02/28 metabolic diseases  ATP-citrate lyase (ACLY)  lipogenesis  ACLY inhibitors  dienyldicarboxylic acid   A brain-to-gut signal controls intestinal fat absorption 期刊论文  OAI收割 NATURE, 2024, 页码: 27 作者:  Lyu, Qianqian;  Xue, Wenzhi;  Liu, Ruixin;  Ma, Qinyun;  Kasaragod, Vikram Babu   |  收藏  |  浏览/下载：95/0  |  提交时间：2024/11/26 Discovery of GPR84 Fluorogenic Probes Based on a Novel Antagonist for GPR84 Bioimaging 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 16 作者:  Xiao, Yufeng;  Chen, Jing;  Li, Shaoxian;  Zhang, Qing;  Liu, Yin   |  收藏  |  浏览/下载：57/0  |  提交时间：2024/08/22