中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [66]
西北高原生物研究所 [18]
地理科学与资源研究... [13]
上海硅酸盐研究所 [8]
合肥物质科学研究院 [5]
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期刊论文 [132]
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2026 [1]
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2022 [7]
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Optics [2]
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Novel thieno[2,3-b]pyridine derivatives protect islet through DRAK2 kinase inhibition
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 301, 页码: 18
作者:
Lian, Kaiyue
;
Li, Ruihan
;
Lu, Yuting
;
Song, Gaolei
;
Zhang, Xinwen
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收藏
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浏览/下载:3/0
  |  
提交时间:2025/12/04
DRAK2
Inhibitor
Thieno[2
b ]pyridine
Diabetes
The enedioic acid analog 326E alleviates metabolic dysfunction-associated steatohepatitis via dual targeting at ACLY and PPARα
期刊论文
OAI收割
CELL METABOLISM, 2025, 卷号: 37, 期号: 11, 页码: 2149-2166
作者:
Xie, Zhifu
;
Cheng, Long
;
Hu, Yue
;
Song, Gaolei
;
Wang, Fan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2026/01/28
Discovery of Novel Tridentate Alkenyl Diacid Derivatives as Potent ATP Citrate Lyase Inhibitors for the Treatment of Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 15, 页码: 15598-15616
作者:
Yang, Yurou
;
Zhai, Jimao
;
Wang, Fan
;
Song, Gaolei
;
Xu, Honghong
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/09/09
Macrophage DGKζ-mediated phosphatidic acid remodeling aggravates acute liver failure
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 8, 页码: 4078-4095
作者:
Miao, Yumeng
;
Lin, Tzuchun
;
Wang, Bianlin
;
Xu, Junyu
;
Li, Chongxian
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/12/04
Xanthohumol derivative
Macrophages
Acute liver failure
Diacylglycerol kinase zeta
Phosphatidic acid
Signal transducer and activator of transcription 3
Interleukin-1/3
Inflammation
A natural small molecule isoginkgetin alleviates hypercholesterolemia and atherosclerosis by targeting ACLY
期刊论文
OAI收割
THERANOSTICS, 2025, 卷号: 15, 期号: 10, 页码: 4325-4344
作者:
Zhang, Zhidan
;
Chen, Meijie
;
Xu, Yitong
;
Wang, Zhihua
;
Liu, Zhenghong
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2025/06/23
Atherosclerosis
Hyperlipidemia
ATP-Citrate lyase (ACLY)
lipid metabolism
Isoginkgetin
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects
期刊论文
OAI收割
DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 1783-1794
作者:
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收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/04/24
safety
tolerability
pharmacokinetics
pharmacodynamics
BGT-002
novel ACLY inhibitor
Investigating the formation and evolution of plant diversity patterns in the Qiangtang Plateau based on phylofloristics approach
期刊论文
OAI收割
GLOBAL ECOLOGY AND CONSERVATION, 2025, 卷号: 58
作者:
Li, Xiaoping
;
Han, Yun
;
Miao, Lei
;
Xu, Hao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/11/27
Qiangtang Plateau
Seed plants
Phylofloristics
Plastid genome
Divergence time
Plant diversity modulates hierarchical responses of carbon cycle processes to warming and grazing in an alpine meadow
期刊论文
OAI收割
JOURNAL OF PLANT ECOLOGY, 2025, 卷号: 18, 期号: 2
作者:
Lu, Wangwang
;
Sun, Jianping
;
Li, Bowen
;
Zhou, Yang
;
Luo, Caiyun
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/11/27
hierarchical responses of carbon cycles
plant diversity
warming
summer and winter grazing
alpine meadow
Qinghai-Tibetan Plateau
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Genetic structure and conservation implications of Lancea tibetica (Mazaceae), a traditional Tibetan medicinal plant endemic to the Qinghai- Tibet Plateau
期刊论文
OAI收割
BMC PLANT BIOLOGY, 2025, 卷号: 25, 期号: 1
作者:
Xia, Mingze
;
Chi, Xiaofeng
;
Yu, Jingya
;
Han, Yun
;
Han, Shuang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/11/27
Lancea tibetica
Allopatric divergence
RAD-seq
Genetic structure
Qinghai-Tibet Plateau
Species distribution modeling
Comparative and phylogenetic analysis of Potentilla and Dasiphora (Rosaceae) based on plastid genome
期刊论文
OAI收割
BMC PLANT BIOLOGY, 2025, 卷号: 25, 期号: 1
作者:
Li, Xiaoping
;
Xu, Hao
;
Yu, Jingya
;
Han, Yun
;
Han, Shuang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/11/27
Potentilla
Dasiphora
Plastid genome
Comparative genomics
Phylogenetic analysis
Cytonuclear discordance