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Tailoring nanovectors for optimal neoantigen vaccine efficacy
期刊论文
OAI收割
JOURNAL OF MATERIALS CHEMISTRY B, 2025, 卷号: 13, 期号: 13, 页码: 4045-4058
作者:
Zheng, Youshi
;
Wang, Bing
;
Cai, Zhixiong
;
Lai, Zisen
;
Yu, Haijun
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/04/24
Self-Oxygenating PROTAC Microneedle for Spatiotemporally-Confined Protein Degradation and Enhanced Glioblastoma Therapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2025, 页码: 13
作者:
Jiang, Xingyu
;
Lai, Yi
;
Xia, Wenzheng
;
Yang, Wenfang
;
Wang, Junjue
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
acid-activatable photodynamic therapy
double-layered microneedle
glioblastoma therapy
light-activatable PROTAC prodrug
protein degradation
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects
期刊论文
OAI收割
DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 1783-1794
作者:
Liu, Yun
;
Yu, Chengyin
;
Zhang, Yifan
;
Xie, Zhifu
;
Wang, Yating
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/04/24
safety
tolerability
pharmacokinetics
pharmacodynamics
BGT-002
novel ACLY inhibitor
Discovery of an Efficacious RET PROTAC Degrader with Enhanced Antiproliferative Activity against Resistant Cancer Cells Harboring RET Solvent-Front Mutations
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 68, 期号: 1, 页码: 753-775
作者:
Zhang, Qian
;
He, Yingqi
;
Rao, Danni
;
He, Rui
;
Yu, Lei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/02/28
Dynamic polyphenol nanoparticles boost cuproptosis-driven metalloimmunotherapy of breast cancer
期刊论文
OAI收割
NANO TODAY, 2024, 卷号: 58, 页码: 12
作者:
Zhang, Huijuan
;
Chen, Fangmin
;
Cheng, Wenhao
;
Lai, Yi
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/10/09
Polyphenol
Cuproptosis
Dynamic covalent bond
Cancer metalloimmunotherapy
Tumor immune microenvironment
Two-stage deep neural network for diagnosing fungal keratitis via in vivo confocal microscopy images
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2024, 卷号: 14, 期号: 1, 页码: 11
作者:
Li, Chun-Peng
;
Dai, Weiwei
;
Xiao, Yun-Peng
;
Qi, Mengying
;
Zhang, Ling-Xiao
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/12/06
Fungal keratitis
Image classification
Neural network
Transformer
AAC theory for ultrasonic vibration-assisted grinding
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY, 2024, 页码: 12
作者:
Hu, Zhongwei
;
Chen, Yue
;
Lai, Zhiyuan
;
Zhang, Yuqiang
;
Yu, Yiqing
  |  
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2024/06/27
Ultrasonic vibration-assisted grinding
Molecular dynamics
Scratch force
Process parameters optimization
Exploring Neighbor Spatial Relationships for Enhanced Lumbar Vertebrae Detection in X-ray Images
期刊论文
OAI收割
ELECTRONICS, 2024, 卷号: 13
作者:
Zeng, Yu
;
Wang, Kun
;
Dai, Lai
;
Wang, Changqing
;
Xiong, Chi
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/11/20
lumbar vertebrae detection
spatial relationship
deep learning
X-ray image analysis
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Hornblendites as a record of differentiation, metasomatism and magma fertility in arc crust
期刊论文
OAI收割
CHEMICAL GEOLOGY, 2024, 卷号: 650, 页码: 15
作者:
Zhu, Ren-Zhi
;
Smith, Daniel J.
;
Wang, Fangyue
;
Qin, Jiang-Feng
;
Zhang, Chao
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/08/29
Fractionation of hornblende
Arc magmas
Metasomatism
Melt-mush interaction
Porphyry copper fertility