中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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近代物理研究所 [96]
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期刊论文 [1139]
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Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10
作者:
Zhang, Chun
;
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Cao, Qing
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Imidazo[2,1-b][1,3,4]thiadiazole
Inhibitory activities
Fluorescence imaging
Zebrafish
SHP2
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
;
Xu, Dong
;
Hoof, Agnes P. C. van
;
Lei, Wei-Hua
;
Liu, Yuan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/07/28
Nonlinear Imaging Detection of Organ Fibrosis in Minute Samples for Early Stage Utilizing Dual-Channel Two-Photon and Second-Harmonic Excitation
期刊论文
OAI收割
BIOSENSORS-BASEL, 2025, 卷号: 15, 期号: 6, 页码: 16
作者:
Yu, Bo-Song
;
Cheng, Qing-Di
;
Liu, Yi-Zhou
;
Zhang, Rui
;
Li, Da-Wei
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
nonlinear imaging
two-photon excitation
second harmonic generation
fibrosis
Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism
期刊论文
OAI收割
CELL METABOLISM, 2025, 卷号: 37, 期号: 5, 页码: 32
作者:
Jiang, Jie
;
Gao, Yuqing
;
Wang, Jiang
;
Huang, Yan
;
Yang, Rong
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
Linking ecosystem services trade-offs, human preferences and future scenario simulations to ecological security patterns: A novel methodology for reconciling conflicting ecological functions
期刊论文
OAI收割
APPLIED GEOGRAPHY, 2025, 卷号: 176, 页码: 103534
作者:
Wu, Qing
;
Cao, Yu
;
Zhang, Yangjian
;
Su, Dan
;
Fang, Xiaoqian
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/03/18
Multi-scenario simulation
OWA model
Ecological security pattern
Trade-offs
PLUS model
Yangtze river delta
Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 653, 页码: 13
作者:
Sun, Ming-Dao
;
Lin, Qin
;
Ramezani, Jahandar
;
Liu, Jiang-Si
;
Lu, Zheng-An
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2025/04/03
Early Cretaceous
Aptian
CA-ID-TIMS geochronology
Astrochronology
Carbon isotope stratigraphy
The Permian-Triassic boundary in the South Yellow Sea, China and its palaeogeographical implications: A case study of CSDP-2 borehole
期刊论文
OAI收割
PALAEOGEOGRAPHY PALAEOCLIMATOLOGY PALAEOECOLOGY, 2025, 卷号: 659, 页码: 14
作者:
Zhu, Xiao-qing
;
Huang, Yu-Xiao
;
Zhang, Hua
;
Wang, Zhi-hao
;
Zhang, Xun-hua
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2025/03/28
The Permian-Triassic boundary
South Yellow Sea
CSDP-2
Conodonts
South China Plate
Multisite modifications of arenes using ketones as removable handles enabled by Pd and norbornene cooperative catalysis
期刊论文
OAI收割
NATURE SYNTHESIS, 2025, 卷号: 4, 期号: 2
作者:
Tao, Kai-Liang
;
Wang, Xing
;
Liu, Huan
;
Chen, Wen-Qing
;
Sun, Yi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/06/04
Berberine Derivative B68 Promotes Tumor Immune Clearance by Dual-Targeting BMI1 for Senescence Induction and CSN5 for PD-L1 Degradation
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 21
作者:
Hu, Hongmei
;
Wang, Qun
;
Yu, Dianping
;
Tao, Xiaoyu
;
Guo, Mengmeng
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2025/02/28
BMI1
colorectal cancer
CSN5
PD-L1
tumor cell senescence