中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [51]
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期刊论文 [135]
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Interpretable data-driven chemometric approach for predicting non-optically active water quality parameters using ultraviolet-visible-near infrared absorption spectroscopy and physical-chemical measurements
期刊论文
OAI收割
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2025, 卷号: 331, 页码: 125768
作者:
Zhao, Yubo
;
Zhang, Zhou
;
Hu, Bingliang
;
Liu, Jiacheng
;
Wang, Xueji
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/03/18
Non-optically active water quality parameters
Ultraviolet-visible-near infrared absorption spectroscopy
Physical-chemical measurements
Yangtze River Basin
eXtreme Gradient Boosting
SHapley Additive exPlanations
Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 13
作者:
Xu, Yali
;
Zhao, Wensi
;
Nie, Hui-Jun
;
Wang, Jiamin
;
Fu, Jingjing
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/05/27
Chemoproteomics
Genetic code expansion
Molecular glue degrader
Photo-crosslinking
Targeted protein degradation
Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679
作者:
Jin, Yuheng
;
Qi, Xuxin
;
Yu, Xiaoli
;
Cheng, Xirui
;
Chen, Boya
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
HDAC7
PROTAC
Selectivity
Hematologic malignancies
Non-enzymatic function
Cavity oscillation drives pattern formation in early mammalian embryos
期刊论文
OAI收割
CELL REPORTS, 2025, 卷号: 44, 期号: 3, 页码: 115342
作者:
Guo, Zheng
;
Yao, Jie
;
Zheng X(郑旭)
;
Cao, Jialing
;
Lv, Xinxin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/07/21
cavity oscillation
EPI/PrE segregation
pattern formation
early mammalian embryos
blastocyst
Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel
Hs
ClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:
Sun, Mingyang
;
Chen, Beijing
;
Teng, Dan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/01
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:
Chen, Jiexuan
;
Wu, Mingfei
;
Mo, Jun
;
Hong, Ju
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/04/01
Discovery of N-Benzylpiperidinol derivatives as USP7 inhibitors against Hematology
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 13
作者:
Pan, Youlu
;
Chen, Haifeng
;
Fu, Jingfeng
;
Zhang, Jingyu
;
Wang, Peipei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/10/21
Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10
作者:
Yu, Qian
;
Gao, Lixin
;
Xu, Linhao
;
Han, Yubing
;
Cao, Yu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/12/11
Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Chen, Beijing
;
Sun, Mingyang
;
Zhang, Chun
;
Huang, Qi
;
Teng, Dan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/12/25