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浏览/检索结果: 共241条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Microbiota-shaped neutrophil senescence regulates sexual dimorphism in bladder cancer 期刊论文  OAI收割 NATURE IMMUNOLOGY, 2025, 卷号: 26, 期号: 5, 页码: 46 作者:  Zhu, Qingchen;  Zhang, Guiheng;  Cao, Ming;  Huang, Huan;  He, Dan   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/06/23 Residue-Selective Inhibitors Discovery via Covalent DNA-Encoded Chemical Libraries with Diverse Warheads 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 18, 页码: 15469-15481 作者:  Wu, Xinyuan;  Pan, Jiayi;  Fan, Rufeng;  Zhang, Yiwei;  Wang, Chao   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/06/23 Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14 作者:  Wu, Xinyuan;  Li, Shunyao;  Liang, Ting;  Yu, Qing;  Zhang, Yiwei   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/06/23 Activity-based protein profiling data  Covalent DNA-encoded chemical library  Covalent ligand selection  Lysine-targeting covalent inhibitors   Recent advances in targeted degradation in the RAS pathway 期刊论文  OAI收割 FUTURE MEDICINAL CHEMISTRY, 2025, 卷号: 17, 期号: 6, 页码: 693-708 作者:  Ge, Zhiming;  Fan, Zisheng;  He, Wei;  Zhou, Guizhen;  Zhou, Yidi   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/04/24 RAS  cancer  mutation  degrader  PROTAC   Targeting the histone reader ZMYND8 inhibits antiandrogen-induced neuroendocrine tumor transdifferentiation of prostate cancer 期刊论文  OAI收割 NATURE CANCER, 2025, 页码: 37 作者:  Wang, Hanling;  Zhang, Sulin;  Pan, Qiang;  Guo, Jiacheng;  Li, Ni   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/05/27 Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2025, 页码: 14 作者:  Wen, Yiming;  Xu, Peijia;  Chen, Yijie;  Meng, Jingyi;  Zheng, Mingyue   |  收藏  |  浏览/下载：20/0  |  提交时间：2025/04/01 p53 Y220C  Covalent stabilizer  Virtual screening  Molecular dynamics  DNA binding  Structure-activity relationship  Cancer therapy   Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel HsClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307 作者:  Sun, Mingyang;  Chen, Beijing;  Teng, Dan;  Zhao, Hongshen;  Liao, Yilie   |  收藏  |  浏览/下载：20/0  |  提交时间：2025/04/01 Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21 作者:  Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/12/25 Synthetic lethal  MSI tumors  WRN inhibitors  Triazolo-pyrimidine derivatives   2-(1-Phenylvinyl)benzoic acid as a highly active leaving group for metal-free glycosylation 期刊论文  OAI收割 ORGANIC CHEMISTRY FRONTIERS, 2025, 页码: 7 作者:  Dai, Qi;  Li, Penghua;  Cao, Yaran;  Xie, Xiangying;  Zhang, Chen   |  收藏  |  浏览/下载：17/0  |  提交时间：2025/04/01 Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy 期刊论文  OAI收割 CANCER MEDICINE, 2025, 卷号: 14, 期号: 1, 页码: 13 作者:  Wang, Kun;  Zhang, Yingying;  Su, Zhaoming;  Wang, Bei;  Zhou, Yuanyang   |  收藏  |  浏览/下载：16/0  |  提交时间：2025/04/01 biomarker  CDC42  clinical response  immunotherapy  pan-cancer