机构

• 上海药物研究所 [12]
• 地球环境研究所 [1]
• 西安光学精密机械研究... [1]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [13]
• 专著章节 [1]

发表日期

• 2023 [3]
• 2022 [3]
• 2021 [4]
• 2020 [1]
• 2019 [1]
• 2018 [1]
• 更多

学科主题

• 数理科学和化学 [1]

筛选

浏览/检索结果: 共14条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF) 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12 作者:  Wu, Xinyu;  Wang, Mingchen;  Cao, Yu;  Xu, Ying;  Yang, Ziqun   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/02/27 O-GlcNAcylation  O-GlcNAc transferase  High-throughput screening  Inhibitor   An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 84, 页码: 117262 作者:  Xie, Yanqiu;  Fan, Shijie;  Ni, Dongxuan;  Wan, Wei;  Xu, Pan   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/27 ATG4B inhibitor  DC-ATG4in  Sorafenib  Hepatocellular Carcinoma  Combination therapy   Chapter Nine - Targeting the super elongation complex for oncogenic transcription driven tumor malignancies: Progress in structure, mechanisms and small molecular inhibitor discovery 专著章节  OAI收割 出自: Advances in Cancer Research, England:Elsevier, 2023, 页码: 387-421 作者:  Wu, Xinyu;  Xie, Yanqiu;  Zhao, Kehao;  Lu, Jing   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/03/26 Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 16, 页码: 11034-11057 作者:  Li, Jiacheng;  Liu, Ting;  Song, Yuanli;  Wang, Mingyu;  Liu, Liping   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/21 High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 2, 页码: 14 作者:  Xiao, Senhao;  Guo, Siqi;  Han, Jie;  Sun, Yanli;  Wang, Mingchen   |  收藏  |  浏览/下载：45/0  |  提交时间：2022/06/15 Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 2, 页码: 470 作者:  Li Wen;  Liao Liping;  Song Ning;  Liu Yanjun;  Ding Yiluan   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/05/22 glyceraldehyde 3-phosphate dehydrogenase  1  2  3  4  6-penta-O-galloyl-β-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125 作者:  Zhang, Huimin;  He, Jixiao;  Hu, Guang;  Zhu, Fei;  Jiang, Hao   |  收藏  |  浏览/下载：70/0  |  提交时间：2022/01/04 Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207 作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens   |  收藏  |  浏览/下载：96/0  |  提交时间：2021/08/17 Drug design targeting active posttranslational modification protein isoforms 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2021, 卷号: 41, 期号: 3, 页码: 1701-1750 作者:  Meng, Fanwang;  Liang, Zhongjie;  Zhao, Kehao;  Luo, Cheng   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/03/22 Allosteric Inhibitor  Covalent Inhibitor  Posttranslational Modifications  Precision Medicine  Protac Protein Degradation  Protein‐  Protein Interactions  Ptm Protein Isoforms  Rational Drug Design   Discovery of a novel 53BP1 inhibitor through AlphaScreen-based high-throughput screening 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 34, 页码: 116054 作者:  Sun, Yanli;  Lu, Haibo;  Fang, Xueyu;  Xiao, Senhao;  Yang, Feng   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/03/21 53BP1-TTD  H4K2Ome2  AlphaScreen  HTS  Novel inhibitor