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Metal-organic frameworks (MOFs) for phototherapy and synergistic phototherapy of cancer
期刊论文
OAI收割
COORDINATION CHEMISTRY REVIEWS, 2025, 卷号: 526, 页码: 23
作者:
Tong, Pei-Hong
;
Yang, Jing-Jie
;
Zhou, Yu-Fan
;
Tang, Yi-Fan
;
Tang, Meng-Tian
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/02/28
Metal-organic frameworks (MOFs)
Phototherapy
Photodynamic therapy
Photothermal therapy
Synergistic therapy
Cancer
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
Optimization and Biological Evaluation of Novel 1
H
-Pyrrolo[2,3-
c
]pyridin Derivatives as Potent and Reversible Lysine Specific Demethylase 1 Inhibitors for the Treatment of Acute Myelogenous Leukemia
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 24, 页码: 22080-22103
作者:
Jiang, Hong
;
Li, Cong
;
Li, Na
;
Sheng, Li
;
Wang, Jingkai
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/01/14
Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 17, 页码: 15220-15245
作者:
Saidahmatov, Abdusaid
;
Li, Jianan
;
Xu, Shihao
;
Hu, Xiaobei
;
Gao, Xiangqian
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/10/21
Characterization and noncovalent inhibition of the K63-deubiquitinase activity of SARS-cov-2 PLpro
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2024, 卷号: 228, 页码: 12
作者:
Liu, Xin
;
Zheng, Miao
;
Zhang, Hongqing
;
Feng, Bo
;
Li, Jiaqi
  |  
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2024/10/21
Discovery of Novel Nonpeptidic and Noncovalent Small Molecule 3CL
pro
Inhibitors as anti-SARS-CoV-2 Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12760-12783
作者:
Jiang, Zhidong
;
Feng, Bo
;
Chen, Lu
;
Nie, Tianqing
;
Chen, Shizhao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/09/26
Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290
作者:
Zheng, Miao
;
Feng, Bo
;
Zhang, Yumin
;
Liu, Xin
;
Zhao, Na
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/08/22
Non-covalent PLpro inhibitors
Antiviral activity
Structural-based drug design
Imidazo[4,5-b]pyridine scaffold
Cross-ancestry genome-wide association studies of brain imaging phenotypes
期刊论文
OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:
Fu, Jilian
;
Zhang, Quan
;
Wang, Jianhua
;
Wang, Meiyun
;
Zhang, Bing
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/06/29
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/05/07
Article Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
期刊论文
OAI收割
CELL REPORTS MEDICINE, 2024, 卷号: 5, 期号: 3, 页码: 25
作者:
Zhu, Weize
;
Hong, Ying
;
Tong, Zhaowei
;
He, Xiaofang
;
Li, Yan
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/06/27