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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [24]
烟台海岸带研究所 [4]
合肥物质科学研究院 [3]
广州生物医药与健康研... [2]
国家天文台 [2]
新疆天文台 [2]
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OAI收割 [42]
内容类型
期刊论文 [42]
发表日期
2026 [1]
2025 [11]
2024 [7]
2023 [4]
2022 [4]
2020 [7]
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Biochemist... [2]
Chemistry [2]
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Brg1-imprinted chromatin status controls effector and memory group 2 innate lymphoid cell metabolism to exacerbate allergic lung inflammation
期刊论文
OAI收割
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2026, 卷号: 157, 期号: 1, 页码: 21
作者:
Tang, Jupei
;
Sun, Hanxiao
;
Chang, Huidan
;
Yuan, Liyun
;
Chen, Yue
  |  
收藏
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浏览/下载:0/0
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提交时间:2026/04/01
Group 2 innate lymphoid cell (ILC2)
Brg1
allergic lung inflammation
ILC2 memory
chromatin accessibility
glycolysis
Filtering and gap-filling strategies in eddy covariance CO2 flux series of mountainous forests: Comparison based on measurements from Qingyuan-Ker Towers
期刊论文
OAI收割
SCIENCE CHINA-EARTH SCIENCES, 2025, 卷号: N/A
作者:
Li, Tongtong
;
Gao, Tian
;
Teng, Dexiong
;
Chen, Zhi
;
Yang, Bai
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收藏
  |  
浏览/下载:2/0
  |  
提交时间:2026/01/21
Complex terrain
Forest ecosystem
Eddy covariance
Friction velocity threshold
Gap-filling
Rational engineering of degradation tail-driven CELMoD-antibody conjugates for precision malignancy therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 12, 页码: 6510-6528
作者:
Guo, Yu
;
Song, Yi
;
Wang, Hanlin
;
Lu, Yang
;
Zhang, Jingyu
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收藏
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浏览/下载:0/0
  |  
提交时间:2026/01/29
Degrader-antibody conjugate
Antibody-drug conjugate
Cereblon E3 ligase modulator
Immunomodulatory drug
Molecular glue
Targeted protein degradation
Multiple myeloma
Hematologic malignancy
Development of Dual FLT3 and CHK1 PROTACs for the Treatment of AML
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 20, 页码: 21939-21961
作者:
Lian, Xuanmin
;
Gao, Yue
;
Du, Wenjing
;
Xu, Chengcheng
;
Dong, Xiaowu
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收藏
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浏览/下载:0/0
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提交时间:2025/12/04
Modular PROTAC/IMiD Bifunctional Molecule Design for the Degradation of Synergistic Targets in the Treatment of Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 20, 页码: 21249-21281
作者:
Jin, Yuheng
;
Liao, Xueyan
;
Zhang, Jingyu
;
Duan, Haiting
;
Xu, Ran
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收藏
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浏览/下载:0/0
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提交时间:2025/12/04
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as novel FLT3/ IRAK4 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 23
作者:
Yuan, Haibin
;
Gao, Yue
;
Wang, Peipei
;
Dong, Xiaowu
;
Li, Jia
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收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/08/20
AML
FLT3/IRAK4 inhibitor
Pyrrolo [2,3-d] pyrimidine
Acquired resistance
Adaptive resistance
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
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收藏
  |  
浏览/下载:37/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Discovery of a Selective and Potent BCL6 PROTAC with Efficacious Antiproliferative Activity for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 19, 页码: 20180-20206
作者:
Yu, Xiaoli
;
Liao, Xueyan
;
Zhang, Jingyu
;
Wang, Hanlin
;
Li, Xian
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收藏
  |  
浏览/下载:0/0
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提交时间:2025/12/04
Discovery of a ubiquitin-specific protease 10 inhibitor with high binding affinity promoting cell apoptosis via down-regulated CDK4 for the treatment of hepatocellular carcinoma
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 17
作者:
Lu, Yang
;
Wang, Wentao
;
Yuan, Cheng
;
Luo, Mengxin
;
Wang, Peipei
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收藏
  |  
浏览/下载:0/0
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提交时间:2025/12/04
HCC
USP10
Deubiquitination
Binding affinity
CDK4
Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities