机构

• 上海药物研究所 [18]
• 烟台海岸带研究所 [4]
• 合肥物质科学研究院 [3]
• 广州生物医药与健康研... [2]
• 国家天文台 [2]
• 新疆天文台 [2]
• 更多

采集方式

• OAI收割 [35]

内容类型

• 期刊论文 [35]

发表日期

• 2025 [5]
• 2024 [7]
• 2023 [4]
• 2022 [4]
• 2020 [7]
• 2019 [4]
• 更多

学科主题

• Biochemist... [2]
• Chemistry [2]

筛选

浏览/检索结果: 共35条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Discovery of pyrrolo[2,3-d]pyrimidine derivatives as novel FLT3/ IRAK4 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 23 作者:  Yuan, Haibin;  Gao, Yue;  Wang, Peipei;  Dong, Xiaowu;  Li, Jia   |  收藏  |  浏览/下载：13/0  |  提交时间：2025/08/20 AML  FLT3/IRAK4 inhibitor  Pyrrolo [2,3-d] pyrimidine  Acquired resistance  Adaptive resistance   Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML) 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17 作者:  Mo, Jun;  Wang, Yuxian;  Pan, Youlu;  Xiao, Qitao;  Zhao, Jinyi   |  收藏  |  浏览/下载：19/0  |  提交时间：2025/08/20 Menin  High binding affinity  Anti-proliferation activity  AML   Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16 作者:  Zeng, Gongruixue;  Xu, Gaoya;  Gao, Lixin;  Zheng, Xiaoli;  Chi, Xinglong   |  收藏  |  浏览/下载：59/0  |  提交时间：2025/04/01 Proteasome inhibitors  Macrocycle  Stability  Anti-cancer activities   Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679 作者:  Jin, Yuheng;  Qi, Xuxin;  Yu, Xiaoli;  Cheng, Xirui;  Chen, Boya   |  收藏  |  浏览/下载：33/0  |  提交时间：2025/06/23 HDAC7  PROTAC  Selectivity  Hematologic malignancies  Non-enzymatic function   Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15 作者:  Chen, Jiexuan;  Wu, Mingfei;  Mo, Jun;  Hong, Ju;  Wang, Wei   |  收藏  |  浏览/下载：57/0  |  提交时间：2025/04/01 Discovery of N-Benzylpiperidinol derivatives as USP7 inhibitors against Hematology 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 13 作者:  Pan, Youlu;  Chen, Haifeng;  Fu, Jingfeng;  Zhang, Jingyu;  Wang, Peipei   |  收藏  |  浏览/下载：62/0  |  提交时间：2024/10/21 Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10 作者:  Yu, Qian;  Gao, Lixin;  Xu, Linhao;  Han, Yubing;  Cao, Yu   |  收藏  |  浏览/下载：69/0  |  提交时间：2024/12/11 Structural simulation and performance evaluation of self-priming electrostatic diesel vehicle emission particle sensor 期刊论文  OAI收割 INSTRUMENTATION SCIENCE & TECHNOLOGY, 2024 作者:  Sun, Qiang;  Wang, Huanqin;  Huang, Gehang;  Jiang, Chufan;  Liu, Jinxin   |  收藏  |  浏览/下载：40/0  |  提交时间：2024/11/20 Calibration platform  diesel exhaust particles  numerical simulation  particulate matter sensor   Simulation of electrostatic particulate matter sensor regeneration based on the particulate deposition patterns 期刊论文  OAI收割 SENSOR REVIEW, 2024 作者:  Liu, Jinxin;  Wang, Huanqin   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/11/20 Particulate matter sensor  Particle deposition  Sensor regeneration  Regeneration device  Ceramic heating element   Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 28 作者:  Duan, Haiting;  Zhang, Jingyu;  Gui, Renzhao;  Lu, Yang;  Pang, Ao   |  收藏  |  浏览/下载：63/0  |  提交时间：2024/08/20