中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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近代物理研究所 [47]
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Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3-c] pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1, 页码: 438-466
作者:
Li, Yang
;
Fang, Yan
;
Chen, Xiaoyu
;
Tong, Linjiang
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
P21-activated kinase 4
Tetrahydrobenzofuro[2
3-c]pyridine
Structure-activity relationship
Allosteric inhibitor
Pharmacokinetics properties
Kinase selectivity
Pancreatic cancer
Immune infiltration
Nitrogen deposition contributed to a global increase in nitrous oxide emissions from forest soils
期刊论文
OAI收割
COMMUNICATIONS EARTH & ENVIRONMENT, 2024, 卷号: 5, 期号: 1, 页码: 532
作者:
Cen, Xiaoyu
;
Mueller, Christoph
;
Kang, Xiaoyan
;
Zhou, Xuhui
;
Zhang, Jinbo
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/10/21
The actin-binding protein drebrin disrupts NF2-LATS kinases complex assembly to facilitate liver tumorigenesis
期刊论文
OAI收割
HEPATOLOGY, 2024, 页码: 20
作者:
Sun, Yang
;
Wei, Henan
;
Yu, Wentao
;
Gao, Haoran
;
Li, Jinhui
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/11/05
Modeling multi-source plastic pollution yield and transport driven by catchment hydrometeorological processes
期刊论文
OAI收割
WATER RESEARCH, 2024, 卷号: 259, 页码: 121863
作者:
Zhang, Yongyong
;
Dou, Ming
;
Cai, Xueliang
;
Han, Bing
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/07/12
Multiple plastic sources
Human development index
Hydrological model
Ensemble modeling
Mulan river catchment
Familial genetic and environmental transmission of depression: A multi-informant twin family study
期刊论文
OAI收割
PSYCH JOURNAL, 2024, 页码: 8
作者:
Ding, Qingwen
;
Zhou, Yueyue
;
Yu, Shuting
;
Cui, Xiaobing
;
Wang, Xiaoyu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/05/13
adolescents
depression
familial transmission
genetics
twins
FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration
期刊论文
OAI收割
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
作者:
Zhang, Xiaoyu
;
Li, Peiwen
;
Zhou, Jin
;
Zhang, Ziliang
;
Wu, Huan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/04/02
Liver sinusoidal endothelial cells
Fenestrae
Liver fibrosis
Cytoskeleton remodeling
FAK
MAPK
Discovery of Pyrido[2,3-
d
]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3986-4006
作者:
Sun, Yaoliang
;
Chen, Manman
;
Han, Yuyan
;
Li, Weiqiang
;
Ma, Xiaoyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/05/07
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/03/25
Cryptic diversity begets challenges and opportunities in biodiversity research
期刊论文
OAI收割
INTEGRATIVE ZOOLOGY, 2024, 页码: 17
作者:
Cheng, Rui
;
Luo, Arong
;
Orr, Michael
;
Ge, Deyan
;
Hou, Zhong'e
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/07
DNA barcoding
genome
integrative taxonomy
morphology
workflow
Transcriptomic and proteomic investigation of the ameliorative effect of total polyphenolic glycoside extract on hepatic fibrosis in Lamiophlomis rotata Kudo via the AGE/RAGE pathway
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 324
作者:
Yang, Congwen
;
Geng, Xiaoyu
;
Wan, Guoguo
;
Song, Liang
;
Wang, Ying
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/11/27