中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Enhanced carbon sequestration in marginal seas through bacterial transformation
期刊论文
OAI收割
WATER RESEARCH, 2025, 卷号: 281, 页码: 7
作者:
Guo, Jinqiang
;
Zhou, Bu
;
Achterberg, Eric P.
;
Shen, Yuan
;
Song, Jinming
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/07/11
Particulate organic matter
Amino acids
Bacterial organic carbon
Heterotrophic transformation
Marginal sea
Two Events with Spectacular Moving Structures in a Failed Solar Filament Eruption
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1
作者:
Ou, Yudi
;
Su, Yingna
;
Zhang, Qingmin
;
Ji, Haisheng
;
Li, Leping
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/07/21
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
Noise Reduction Method for Radio Astronomy Single Station Observation Based on Wavelet Transform and Mathematical Morphology
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Qin, Ming-Wei
;
Tang, Rui
;
Zhou, Ying-Hui
;
Lan, Chang-Jun
;
Fu, Wen-Hao
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/07/03
methods: data analysis
techniques: image processing
techniques: spectroscopic
Sun: radio radiation
methods: numerical
Design and synthesis of GRPR-targeted PET probes based on Dar derivatives for imaging of prostate cancer
期刊论文
OAI收割
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2025, 卷号: 67, 页码: 9
作者:
Luo, Xiangning
;
Luo, Renli
;
Zhou, Yuanyuan
;
Jiang, Yuanpeng
;
Han, Cong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Gastrin-releasing peptide receptor
68Ga
Dar chelator
Positron emission tomography
Imaging probe
Discovery of TBK1Molecular Glue Degraders as a Potential Strategy for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 12, 页码: 12862-12880
作者:
Guo, Jing
;
Tang, Haotian
;
Zhao, Wenchao
;
Li, Yong
;
Song, Shukai
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Nonlinear Imaging Detection of Organ Fibrosis in Minute Samples for Early Stage Utilizing Dual-Channel Two-Photon and Second-Harmonic Excitation
期刊论文
OAI收割
BIOSENSORS-BASEL, 2025, 卷号: 15, 期号: 6, 页码: 16
作者:
Yu, Bo-Song
;
Cheng, Qing-Di
;
Liu, Yi-Zhou
;
Zhang, Rui
;
Li, Da-Wei
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
nonlinear imaging
two-photon excitation
second harmonic generation
fibrosis
Hydroxyapatite-loaded cobalt nanoparticles catalyze the 5-hydroxyme thylfurfural green oxidation to 2,5-furandicarboxylic acid under mild conditions (vol 273, 117490, 2025)
期刊论文
OAI收割
POLYHEDRON, 2025, 卷号: 274, 页码: 1
作者:
Song, Yadong
;
Gao, Kun
;
Zhou, Luxiao
;
Yu, Huahua
;
Xing, Ronge
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/07/11