中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of pyrrolo[2,3-d]pyrimidine derivatives as novel FLT3/ IRAK4 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 23
作者:
Yuan, Haibin
;
Gao, Yue
;
Wang, Peipei
;
Dong, Xiaowu
;
Li, Jia
  |  
收藏
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浏览/下载:1/0
  |  
提交时间:2025/08/20
AML
FLT3/IRAK4 inhibitor
Pyrrolo [2,3-d] pyrimidine
Acquired resistance
Adaptive resistance
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Historical trends and future projections of compound cloudy-rainy events during the global winter wheat harvest phase
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2025, 卷号: 371, 页码: 110637
作者:
  |  
收藏
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浏览/下载:12/0
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提交时间:2025/07/18
Compound cloudy-rainy events
Winter wheat
Harvest phase
Climate change
From molecular characteristics to microbial functions: DOM transformation driven by sewage sludge compost in mine topsoil revealed by a large-scale field study
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2025, 卷号: 517, 页码: 164559
作者:
Dong, Yuecen
;
Jia, Yufeng
;
Xu, Xingkun
;
Yu, Mingdong
;
Zhou, Ping
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/07/18
Sewage sludge compost
Dissolved organic matter
Field experiments
Fourier-transform ion cyclotron resonance
mass spectrometry
Functional annotation
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
;
Xu, Dong
;
Hoof, Agnes P. C. van
;
Lei, Wei-Hua
;
Liu, Yuan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/07/28
Investigation on approaches for little temperature difference heat exchange for the energy storage system with CO2 transcritical thermodynamic cycles
期刊论文
OAI收割
JOURNAL OF ENERGY STORAGE, 2025, 卷号: 124, 页码: 21
作者:
Pan, Lisheng
;
Dong, Yuehua
;
Shi, Weixiu
;
Zhou, Junwei
;
Wei, Xiaolin
  |  
收藏
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浏览/下载:15/0
  |  
提交时间:2025/07/22
Energy storage
Multi-stage heat transfer
Heat exchange of contact and phase
transformation
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
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收藏
  |  
浏览/下载:33/0
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提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
Gastrodia elata
Blume extract alleviates sepsis-induced lung injury by suppressing IL-23/IL-17 A axis
期刊论文
OAI收割
FITOTERAPIA, 2025, 卷号: 184, 页码: 12
作者:
Dong, Huiqing
;
Zhang, Yun
;
Zhou, Yang
;
Zhang, Menghui
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Gastrodia elata Blume extract
Sepsis-induced lung injury
IL-23/IL-17 A axis
Neutrophil infiltration
Triconnarins A-D: Four Secophragmalin-Type Limonoids from the Twigs and Leaves of
Trichilia connaroides
期刊论文
OAI收割
ORGANIC LETTERS, 2025, 卷号: 27, 期号: 25, 页码: 6772-6776
作者:
Xu, Jia-Xin
;
Zhao, Hai-Yang
;
Li, Xiao-Zhou
;
Li, Zhi-Ying
;
Shen, Tao
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收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Discovery of TBK1Molecular Glue Degraders as a Potential Strategy for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 12, 页码: 12862-12880
作者:
Guo, Jing
;
Tang, Haotian
;
Zhao, Wenchao
;
Li, Yong
;
Song, Shukai
  |  
收藏
  |  
浏览/下载:3/0
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提交时间:2025/08/20