中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海应用物理研究... [178]
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期刊论文 [1944]
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Investigation on approaches for little temperature difference heat exchange for the energy storage system with CO2 transcritical thermodynamic cycles
期刊论文
OAI收割
JOURNAL OF ENERGY STORAGE, 2025, 卷号: 124, 页码: 21
作者:
Pan, Lisheng
;
Dong, Yuehua
;
Shi, Weixiu
;
Zhou, Junwei
;
Wei, Xiaolin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/07/22
Energy storage
Multi-stage heat transfer
Heat exchange of contact and phase
transformation
De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
;
Shan, Yiming
;
Huang, Lujia
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Neuronal CCL2 responds to hyperglycaemia and contributes to anxiety disorders in the context of diabetes
期刊论文
OAI收割
NATURE METABOLISM, 2025, 卷号: 7, 期号: 5, 页码: 39
作者:
Pan, Kaijun
;
Gao, Yanan
;
Zong, Haichao
;
Zhang, Yongmei
;
Qi, Yingbei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/06/23
Residue-Selective Inhibitors Discovery via Covalent DNA-Encoded Chemical Libraries with Diverse Warheads
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 18, 页码: 15469-15481
作者:
Wu, Xinyuan
;
Pan, Jiayi
;
Fan, Rufeng
;
Zhang, Yiwei
;
Wang, Chao
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/06/23
Threshold response of arbuscular mycorrhizal mycelial respiration to a nitrogen addition gradient in an alpine grassland
期刊论文
OAI收割
FUNCTIONAL ECOLOGY, 2025, 卷号: N/A
作者:
Wang, Quan-Cheng
;
Shi, Jiawei
;
Wang, Jinsong
;
Pan, Junxiao
;
Ma, Fangfang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/04/21
alpine grassland
arbuscular mycorrhizal mycelial respiration
mesh exclusion method
N addition gradient
threshold
Targeting the histone reader ZMYND8 inhibits antiandrogen-induced neuroendocrine tumor transdifferentiation of prostate cancer
期刊论文
OAI收割
NATURE CANCER, 2025, 页码: 37
作者:
Wang, Hanling
;
Zhang, Sulin
;
Pan, Qiang
;
Guo, Jiacheng
;
Li, Ni
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/05/27
Self-Oxygenating PROTAC Microneedle for Spatiotemporally-Confined Protein Degradation and Enhanced Glioblastoma Therapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2025, 页码: 13
作者:
Jiang, Xingyu
;
Lai, Yi
;
Xia, Wenzheng
;
Yang, Wenfang
;
Wang, Junjue
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/04/24
acid-activatable photodynamic therapy
double-layered microneedle
glioblastoma therapy
light-activatable PROTAC prodrug
protein degradation
Science objectives of the Einstein Probe mission
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 3
作者:
Yuan, Weimin
;
Dai, Lixin
;
Feng, Hua
;
Jin, Chichuan
;
Jonker, Peter
  |  
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2025/02/13
Einstein Probe
X-ray astronomy
X-ray telescopes
time-domain astronomy
transients
variability
Metal-organic frameworks (MOFs) for phototherapy and synergistic phototherapy of cancer
期刊论文
OAI收割
COORDINATION CHEMISTRY REVIEWS, 2025, 卷号: 526, 页码: 23
作者:
Tong, Pei-Hong
;
Yang, Jing-Jie
;
Zhou, Yu-Fan
;
Tang, Yi-Fan
;
Tang, Meng-Tian
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2025/02/28
Metal-organic frameworks (MOFs)
Phototherapy
Photodynamic therapy
Photothermal therapy
Synergistic therapy
Cancer